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Ictal Generalized EEG Attenuation (IGEA) and hypopnea in a child with occipital type 1 cortical dysplasia – Is it a biomarker for SUDEP?
An interesting association of ictal hypopnea and ictal generalized EEG attenuation (IGEA) as possible marker of sudden unexpected death in epilepsy (SUDEP) is reported. We describe a 5-years-old girl with left focal seizures with secondary generalization due to right occipital cortical dysplasia pre...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350194/ https://www.ncbi.nlm.nih.gov/pubmed/25745325 http://dx.doi.org/10.4103/0972-2327.144279 |
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author | Chaitanya, Ganne Santosh, N. Subbareddy Velmurugan, Jayabal Arivazhagan, Arima Bharath, Rose D. Mahadevan, Anita Nagappa, Madhu Bindu, Parayil S Rao, Malla Bhaskara Taly, Arun B. Satishchandra, Parthasarathy Sinha, Sanjib |
author_facet | Chaitanya, Ganne Santosh, N. Subbareddy Velmurugan, Jayabal Arivazhagan, Arima Bharath, Rose D. Mahadevan, Anita Nagappa, Madhu Bindu, Parayil S Rao, Malla Bhaskara Taly, Arun B. Satishchandra, Parthasarathy Sinha, Sanjib |
author_sort | Chaitanya, Ganne |
collection | PubMed |
description | An interesting association of ictal hypopnea and ictal generalized EEG attenuation (IGEA) as possible marker of sudden unexpected death in epilepsy (SUDEP) is reported. We describe a 5-years-old girl with left focal seizures with secondary generalization due to right occipital cortical dysplasia presenting with ictal hypopnea and IGEA. She had repeated episodes of the ictal apnoea in the past requiring ventilator support and intensive care unit (ICU) admission during episodes of status epilepticus. The IGEA lasted for 0.26-4.68 seconds coinciding with the ictal hypopnea during which both clinical seizure and electrical epileptic activity stopped. Review of literature showed correlation between post-ictal apnoea and post ictal generalized EEG suppression and increased risk for SUDEP. The report adds to the growing body of literature on peri-ictal apnea, about its association with IGEA might be considered as a marker for SUDEP. She is seizure free for 4 months following surgery. |
format | Online Article Text |
id | pubmed-4350194 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-43501942015-03-05 Ictal Generalized EEG Attenuation (IGEA) and hypopnea in a child with occipital type 1 cortical dysplasia – Is it a biomarker for SUDEP? Chaitanya, Ganne Santosh, N. Subbareddy Velmurugan, Jayabal Arivazhagan, Arima Bharath, Rose D. Mahadevan, Anita Nagappa, Madhu Bindu, Parayil S Rao, Malla Bhaskara Taly, Arun B. Satishchandra, Parthasarathy Sinha, Sanjib Ann Indian Acad Neurol Case Report An interesting association of ictal hypopnea and ictal generalized EEG attenuation (IGEA) as possible marker of sudden unexpected death in epilepsy (SUDEP) is reported. We describe a 5-years-old girl with left focal seizures with secondary generalization due to right occipital cortical dysplasia presenting with ictal hypopnea and IGEA. She had repeated episodes of the ictal apnoea in the past requiring ventilator support and intensive care unit (ICU) admission during episodes of status epilepticus. The IGEA lasted for 0.26-4.68 seconds coinciding with the ictal hypopnea during which both clinical seizure and electrical epileptic activity stopped. Review of literature showed correlation between post-ictal apnoea and post ictal generalized EEG suppression and increased risk for SUDEP. The report adds to the growing body of literature on peri-ictal apnea, about its association with IGEA might be considered as a marker for SUDEP. She is seizure free for 4 months following surgery. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4350194/ /pubmed/25745325 http://dx.doi.org/10.4103/0972-2327.144279 Text en Copyright: © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Chaitanya, Ganne Santosh, N. Subbareddy Velmurugan, Jayabal Arivazhagan, Arima Bharath, Rose D. Mahadevan, Anita Nagappa, Madhu Bindu, Parayil S Rao, Malla Bhaskara Taly, Arun B. Satishchandra, Parthasarathy Sinha, Sanjib Ictal Generalized EEG Attenuation (IGEA) and hypopnea in a child with occipital type 1 cortical dysplasia – Is it a biomarker for SUDEP? |
title | Ictal Generalized EEG Attenuation (IGEA) and hypopnea in a child with occipital type 1 cortical dysplasia – Is it a biomarker for SUDEP? |
title_full | Ictal Generalized EEG Attenuation (IGEA) and hypopnea in a child with occipital type 1 cortical dysplasia – Is it a biomarker for SUDEP? |
title_fullStr | Ictal Generalized EEG Attenuation (IGEA) and hypopnea in a child with occipital type 1 cortical dysplasia – Is it a biomarker for SUDEP? |
title_full_unstemmed | Ictal Generalized EEG Attenuation (IGEA) and hypopnea in a child with occipital type 1 cortical dysplasia – Is it a biomarker for SUDEP? |
title_short | Ictal Generalized EEG Attenuation (IGEA) and hypopnea in a child with occipital type 1 cortical dysplasia – Is it a biomarker for SUDEP? |
title_sort | ictal generalized eeg attenuation (igea) and hypopnea in a child with occipital type 1 cortical dysplasia – is it a biomarker for sudep? |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350194/ https://www.ncbi.nlm.nih.gov/pubmed/25745325 http://dx.doi.org/10.4103/0972-2327.144279 |
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