Hypertension and diabetes as risk factors for dementia: A secondary post-hoc analysis from north-west India

INTRODUCTION: A relation between midlife risk factors (hypertension and diabetes) and dementia has been studied in past and an association has been documented, in spite of some studies pointing to the contrary. MATERIALS AND METHODS: The study was based on post-hoc analysis of data obtained from a s...

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Autores principales: Raina, Sunil Kumar, Chander, Vishav, Raina, Sujeet, Kumar, Dinesh, Grover, Ashoo, Bhardwaj, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350217/
https://www.ncbi.nlm.nih.gov/pubmed/25745313
http://dx.doi.org/10.4103/0972-2327.151045
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author Raina, Sunil Kumar
Chander, Vishav
Raina, Sujeet
Kumar, Dinesh
Grover, Ashoo
Bhardwaj, Ashok
author_facet Raina, Sunil Kumar
Chander, Vishav
Raina, Sujeet
Kumar, Dinesh
Grover, Ashoo
Bhardwaj, Ashok
author_sort Raina, Sunil Kumar
collection PubMed
description INTRODUCTION: A relation between midlife risk factors (hypertension and diabetes) and dementia has been studied in past and an association has been documented, in spite of some studies pointing to the contrary. MATERIALS AND METHODS: The study was based on post-hoc analysis of data obtained from a study conducted on an elderly population (60 years and above) from selected geographical areas (migrant, urban, rural and tribal) of the Himachal Pradesh state in North-West India. RESULTS: Analysis of variance revealed an effect of risk factors on cognitive scores; however, post hoc Tukey's honest significant difference (HSD) test revealed that only hypertensives’ demonstrated higher chances of scoring lower on cognitive measures. DISCUSSION: The possibility that hypertension and diabetes affect dementia needs further evaluation, more so in Indian context.
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spelling pubmed-43502172015-03-05 Hypertension and diabetes as risk factors for dementia: A secondary post-hoc analysis from north-west India Raina, Sunil Kumar Chander, Vishav Raina, Sujeet Kumar, Dinesh Grover, Ashoo Bhardwaj, Ashok Ann Indian Acad Neurol Original Article INTRODUCTION: A relation between midlife risk factors (hypertension and diabetes) and dementia has been studied in past and an association has been documented, in spite of some studies pointing to the contrary. MATERIALS AND METHODS: The study was based on post-hoc analysis of data obtained from a study conducted on an elderly population (60 years and above) from selected geographical areas (migrant, urban, rural and tribal) of the Himachal Pradesh state in North-West India. RESULTS: Analysis of variance revealed an effect of risk factors on cognitive scores; however, post hoc Tukey's honest significant difference (HSD) test revealed that only hypertensives’ demonstrated higher chances of scoring lower on cognitive measures. DISCUSSION: The possibility that hypertension and diabetes affect dementia needs further evaluation, more so in Indian context. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4350217/ /pubmed/25745313 http://dx.doi.org/10.4103/0972-2327.151045 Text en Copyright: © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Raina, Sunil Kumar
Chander, Vishav
Raina, Sujeet
Kumar, Dinesh
Grover, Ashoo
Bhardwaj, Ashok
Hypertension and diabetes as risk factors for dementia: A secondary post-hoc analysis from north-west India
title Hypertension and diabetes as risk factors for dementia: A secondary post-hoc analysis from north-west India
title_full Hypertension and diabetes as risk factors for dementia: A secondary post-hoc analysis from north-west India
title_fullStr Hypertension and diabetes as risk factors for dementia: A secondary post-hoc analysis from north-west India
title_full_unstemmed Hypertension and diabetes as risk factors for dementia: A secondary post-hoc analysis from north-west India
title_short Hypertension and diabetes as risk factors for dementia: A secondary post-hoc analysis from north-west India
title_sort hypertension and diabetes as risk factors for dementia: a secondary post-hoc analysis from north-west india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350217/
https://www.ncbi.nlm.nih.gov/pubmed/25745313
http://dx.doi.org/10.4103/0972-2327.151045
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