Melatonin prevents morphine-induced hyperalgesia and tolerance in rats: role of protein kinase C and N-methyl-D-aspartate receptors

BACKGROUND: Morphine-induced hyperalgesia and tolerance significantly limits its clinical use in relieving acute and chronic pain. Melatonin, a pineal gland neurohormone, has been shown to participate in certain neuropsychopharmacological actions. The present study investigated the effect of melaton...

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Detalles Bibliográficos
Autores principales: Song, Li, Wu, Chaoran, Zuo, Yunxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350305/
https://www.ncbi.nlm.nih.gov/pubmed/25745356
http://dx.doi.org/10.1186/1471-2253-15-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350305/
https://www.ncbi.nlm.nih.gov/pubmed/25745356
http://dx.doi.org/10.1186/1471-2253-15-12

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