The progesterone antagonist mifepristone/RU486 blocks the negative effect on life span caused by mating in female Drosophila

Mating causes decreased life span in female Drosophila. Here we report that mifepristone blocked this effect, yielding life span increases up to +68%. Drug was fed to females after mating, in the absence of males, demonstrating function in females. Mifepristone did not increase life span of virgin f...

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Detalles Bibliográficos
Autores principales: Landis, Gary N., Salomon, Matthew P., Keroles, Daniel, Brookes, Nicholas, Sekimura, Troy, Tower, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350324/
https://www.ncbi.nlm.nih.gov/pubmed/25614682

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