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Role of p38 mitogen-activated protein kinase in vascular endothelial aging: Interaction with Arginase-II and S6K1 signaling pathway
p38 mitogen-activated protein kinase (p38) regulates cellular senescence and senescence-associated secretory phenotype (SASP), i.e., secretion of cytokines and/or chemokines. Previous work showed that augmented arginase-II (Arg-II) and S6K1 interact with each other to promote endothelial senescence...
Autores principales: | Wu, Zongsong, Yu, Yi, Liu, Chang, Xiong, Yuyan, Montani, Jean-Pierre, Yang, Zhihong, Ming, Xiu-Fen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350325/ https://www.ncbi.nlm.nih.gov/pubmed/25635535 |
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