Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status

The presence of cancer stem cells (CSCs) is linked to preexisting or acquired drug resistance and tumor relapse. Therefore, targeting both differentiated tumor cells and CSCs was suggested as an effective approach for non-small cell lung cancer (NSCLC) treatment. After screening of chemotherapeutic...

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Detalles Bibliográficos
Autores principales: Xiao, Zhiguang, Sperl, Bianca, Ullrich, Axel, Knyazev, Pjotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350329/
https://www.ncbi.nlm.nih.gov/pubmed/25375092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350329/
https://www.ncbi.nlm.nih.gov/pubmed/25375092

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