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GluA2 is rapidly edited at the Q/R site during neural differentiation in vitro

The majority of AMPA receptors in the adult brain contain GluA2 subunits, which can be edited at the Q/R site, changing a glutamine to an arginine within the ion pore. Q/R editing renders AMPARs virtually Ca(2+)-impermeable, which is important for normal AMPA receptor function. Thus, all GluA2 subun...

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Detalles Bibliográficos
Autores principales:	Pachernegg, Svenja, Münster, Yvonne, Muth-Köhne, Elke, Fuhrmann, Gloria, Hollmann, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350408/ https://www.ncbi.nlm.nih.gov/pubmed/25798088 http://dx.doi.org/10.3389/fncel.2015.00069

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