Cargando…

Investigation of blood mRNA biomarkers for suicidality in an independent sample

Changes in the blood expression levels of SAT1, PTEN, MAP3K3 and MARCKS genes have been reported as biomarkers of high versus low suicidality state (Le-Niculescu et al.). Here, we investigate these expression biomarkers in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study, of patients...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mullins, N, Hodgson, K, Tansey, K E, Perroud, N, Maier, W, Mors, O, Rietschel, M, Hauser, J, Henigsberg, N, Souery, D, Aitchison, K, Farmer, A, McGuffin, P, Breen, G, Uher, R, Lewis, C M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350518/ https://www.ncbi.nlm.nih.gov/pubmed/25350297 http://dx.doi.org/10.1038/tp.2014.112

Ejemplares similares

Exploring the role of drug-metabolising enzymes in antidepressant side effects
por: Hodgson, Karen, et al.
Publicado: (2015)

Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables
por: Iniesta, Raquel, et al.
Publicado: (2018)

Suicidal ideation during treatment of depression with escitalopram and nortriptyline in Genome-Based Therapeutic Drugs for Depression (GENDEP): a clinical trial
por: Perroud, Nader, et al.
Publicado: (2009)

Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)
por: Ren, Hongyan, et al.
Publicado: (2018)

Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: Clinical description and the role of the 5-HTTLPR
por: Strohmaier, Jana, et al.
Publicado: (2011)

Genetic Predictors of Response to Serotonergic and Noradrenergic Antidepressants in Major Depressive Disorder: A Genome-Wide Analysis of Individual-Level Data and a Meta-Analysis
por: Tansey, Katherine E., et al.
Publicado: (2012)

Familiality and SNP heritability of age at onset and episodicity in major depressive disorder
por: Ferentinos, P., et al.
Publicado: (2015)

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genome-wide association and polygenic scoring study
por: Mullins, Niamh, et al.
Publicado: (2014)

Genomewide Association Scan of Suicidal Thoughts and Behaviour in Major Depression
por: Schosser, Alexandra, et al.
Publicado: (2011)

Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder
por: Rucker, James J.H., et al.
Publicado: (2016)

Interaction between stress and the BDNF Val66Met polymorphism in depression: a systematic review and meta-analysis
por: Hosang, Georgina M, et al.
Publicado: (2014)

Genome-wide approaches to antidepressant treatment: working towards understanding and predicting response
por: Hodgson, Karen, et al.
Publicado: (2012)

The relationship between schizophrenia and rheumatoid arthritis revisited: Genetic and epidemiological analyses
por: Euesden, Jack, et al.
Publicado: (2015)

Candidate Genes Expression Profile Associated with Antidepressants Response in the GENDEP Study: Differentiating between Baseline ‘Predictors' and Longitudinal ‘Targets'
por: Cattaneo, Annamaria, et al.
Publicado: (2013)

Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study
por: Hung, Chi-Fa, et al.
Publicado: (2014)

DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP
por: Powell, T R, et al.
Publicado: (2013)

Meta-analysis of CYP2C19 and CYP2D6 metabolic activity on antidepressant response from 13 clinical studies
por: Li, Danyang, et al.
Publicado: (2023)

The Depression Network (DeNT) Study: methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study
por: Farmer, Anne, et al.
Publicado: (2004)

Genome Wide Association Analysis of Copy Number Variation in Recurrent Depressive Disorder
por: Rucker, James J.H., et al.
Publicado: (2011)

Methodology for clinical genotyping of CYP2D6 and CYP2C19
por: Carvalho Henriques, Beatriz, et al.
Publicado: (2021)

Correction: Methodology for clinical genotyping of CYP2D6 and CYP2C19
por: Henriques, Beatriz Carvalho, et al.
Publicado: (2022)

Childhood maltreatment and the medical morbidity in bipolar disorder: a case–control study
por: Hosang, Georgina M., et al.
Publicado: (2017)

A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder
por: Hung, Chi-Fa, et al.
Publicado: (2015)

Polygenic interactions with environmental adversity in the aetiology of major depressive disorder
por: Mullins, N., et al.
Publicado: (2016)

Genetic and other risk factors for suicidal ideation and the relationship with depression
por: Dutta, R., et al.
Publicado: (2017)

Recent development in health educations in schools in Northern Ireland.
por: McGuffin, S. J.
Publicado: (1978)

Drinking patterns of young people in Northern Ireland.
por: McGuffin, S. J.
Publicado: (1979)

Irving Gottesman: American psychologist and behaviour geneticist who radically changed traditional views of schizophrenia
por: McGuffin, Peter
Publicado: (2017)

ReFOLD: a server for the refinement of 3D protein models guided by accurate quality estimates
por: Shuid, Ahmad N., et al.
Publicado: (2017)

Diagnosing migraine in research and clinical settings: The validation of the Structured Migraine Interview (SMI)
por: Samaan, Zainab, et al.
Publicado: (2010)

Psiquiatría : Notas para estudiantes de medicina/
por: McGuffin, P. (Peter)
Publicado: (1992)

Benchmarking consensus model quality assessment for protein fold recognition
por: McGuffin, Liam J
Publicado: (2007)

Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals()
por: Rivera, Margarita, et al.
Publicado: (2017)

Identifying the Common Genetic Basis of Antidepressant Response
por: Pain, Oliver, et al.
Publicado: (2021)

Putative Transcriptomic Biomarkers in the Inflammatory Cytokine Pathway Differentiate Major Depressive Disorder Patients from Control Subjects and Bipolar Disorder Patients
por: Powell, Timothy R., et al.
Publicado: (2014)

Safe Use of Herbal Kelp Supplements
por: McGuffin, Michael, et al.
Publicado: (2007)

The successful search for genetic loci associated with depression
por: Rivera, Margarita, et al.
Publicado: (2015)

A Polymorphism Associated with Depressive Disorders Differentially Regulates Brain Derived Neurotrophic Factor Promoter IV Activity
por: Hing, Benjamin, et al.
Publicado: (2012)

Chipping away at major depressive disorder
por: Rucker, James JH, et al.
Publicado: (2014)

Methods for the Refinement of Protein Structure 3D Models
por: Adiyaman, Recep, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_42m4g1r5u5rlma69nu2ud256tc