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Quantitative Chemoproteomics for Site-Specific Analysis of Protein Alkylation by 4-Hydroxy-2-Nonenal in Cells

[Image: see text] Protein alkylation by 4-hydroxy-2-nonenal (HNE), an endogenous lipid derived electrophile, contributes to stress signaling and cellular toxicity. Although previous work has identified protein targets for HNE alkylation, the sequence specificity of alkylation and dynamics in a cellu...

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Detalles Bibliográficos
Autores principales:	Yang, Jing, Tallman, Keri A., Porter, Ned A., Liebler, Daniel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350606/ https://www.ncbi.nlm.nih.gov/pubmed/25654326 http://dx.doi.org/10.1021/ac504685y

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