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Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy
The study aimed to uncover the risk factors for the new defined pancreatic fistula (PF) and clinical related PF (CR-PF) after pancreaticoduodenectomy (PD) surgery and to evaluate the medico-economic effect of patients. A total of 412 patients were classified into two groups according to different cr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350616/ https://www.ncbi.nlm.nih.gov/pubmed/25788941 http://dx.doi.org/10.1155/2015/917689 |
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author | Huang, Renping Liu, Bing Chen, Hua Bai, Xuewei Kong, Rui Wang, Gang Wang, Yongwei Sun, Bei Guan, Yinghui |
author_facet | Huang, Renping Liu, Bing Chen, Hua Bai, Xuewei Kong, Rui Wang, Gang Wang, Yongwei Sun, Bei Guan, Yinghui |
author_sort | Huang, Renping |
collection | PubMed |
description | The study aimed to uncover the risk factors for the new defined pancreatic fistula (PF) and clinical related PF (CR-PF) after pancreaticoduodenectomy (PD) surgery and to evaluate the medico-economic effect of patients. A total of 412 patients were classified into two groups according to different criteria, PF and NOPF according to PF occurrence: CR-PF (grades B and C) and NOCR-PF (grade A) based on PF severity. A total of 28 factors were evaluated by univariate and multivariate logistic regression test. Hospital charges and stays of these patients were assessed. The results showed that more hospital stages and charges are needed for patients in PF and CR-PF groups than in NOPF and NOCR-PF groups (P < 0.05). The excessive drinking, soft remnant pancreas, preoperative albumin, and intraoperative blood transfusion are risk factors affecting both PF and CR-PF incidence. More professional surgeons can effectively reduce the PF and CR-PF incidence. Patients with PF and CR-PF need more hospital costs and stages than that in NOPF and NOCR-PF groups. It is critical that surgeons know the risk factors related to PF and CR-PF so as to take corresponding therapeutic regimens for each patient. |
format | Online Article Text |
id | pubmed-4350616 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43506162015-03-18 Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy Huang, Renping Liu, Bing Chen, Hua Bai, Xuewei Kong, Rui Wang, Gang Wang, Yongwei Sun, Bei Guan, Yinghui Gastroenterol Res Pract Research Article The study aimed to uncover the risk factors for the new defined pancreatic fistula (PF) and clinical related PF (CR-PF) after pancreaticoduodenectomy (PD) surgery and to evaluate the medico-economic effect of patients. A total of 412 patients were classified into two groups according to different criteria, PF and NOPF according to PF occurrence: CR-PF (grades B and C) and NOCR-PF (grade A) based on PF severity. A total of 28 factors were evaluated by univariate and multivariate logistic regression test. Hospital charges and stays of these patients were assessed. The results showed that more hospital stages and charges are needed for patients in PF and CR-PF groups than in NOPF and NOCR-PF groups (P < 0.05). The excessive drinking, soft remnant pancreas, preoperative albumin, and intraoperative blood transfusion are risk factors affecting both PF and CR-PF incidence. More professional surgeons can effectively reduce the PF and CR-PF incidence. Patients with PF and CR-PF need more hospital costs and stages than that in NOPF and NOCR-PF groups. It is critical that surgeons know the risk factors related to PF and CR-PF so as to take corresponding therapeutic regimens for each patient. Hindawi Publishing Corporation 2015 2015-02-19 /pmc/articles/PMC4350616/ /pubmed/25788941 http://dx.doi.org/10.1155/2015/917689 Text en Copyright © 2015 Renping Huang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Huang, Renping Liu, Bing Chen, Hua Bai, Xuewei Kong, Rui Wang, Gang Wang, Yongwei Sun, Bei Guan, Yinghui Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
title | Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
title_full | Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
title_fullStr | Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
title_full_unstemmed | Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
title_short | Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
title_sort | risk factors and medico-economic effect of pancreatic fistula after pancreaticoduodenectomy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350616/ https://www.ncbi.nlm.nih.gov/pubmed/25788941 http://dx.doi.org/10.1155/2015/917689 |
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