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Altered Viral Replication and Cell Responses by Inserting MicroRNA Recognition Element into PB1 in Pandemic Influenza A Virus (H1N1) 2009

Objective. MicroRNAs (miRNAs) are endogenous noncoding RNAs that spatiotemporally modulate mRNAs in a posttranscriptional manner. Engineering mutant viruses by inserting cell-specific miRNA recognition element (MRE) into viral genome may alter viral infectivity and host responses in vital tissues an...

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Detalles Bibliográficos
Autores principales:	Shen, Xiaoyue, Sun, Wenkui, Shi, Yi, Xing, Zheng, Su, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350627/ https://www.ncbi.nlm.nih.gov/pubmed/25788763 http://dx.doi.org/10.1155/2015/976575

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