Cargando…

Reduced Expression of the Antigen Processing Machinery Components TAP2, LMP2, and LMP7 in Tonsillar and Base of Tongue Cancer and Implications for Clinical Outcome()

OBJECTIVES: Patients with human papillomavirus (HPV)–positive tonsillar squamous cell carcinoma (TSCC) and base of tongue squamous cell carcinoma (BOTSCC) have a better clinical outcome than those with corresponding HPV-negative tumors. Moreover, there is a strong positive correlation between absent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tertipis, Nikolaos, Haeggblom, Linnea, Grün, Nathalie, Nordfors, Cecilia, Näsman, Anders, Dalianis, Tina, Ramqvist, Torbjörn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350639/ https://www.ncbi.nlm.nih.gov/pubmed/25749172 http://dx.doi.org/10.1016/j.tranon.2014.11.002

Ejemplares similares

Correlation of LMP10 Expression and Clinical Outcome in Human Papillomavirus (HPV) Positive and HPV-Negative Tonsillar and Base of Tongue Cancer
por: Tertipis, Nikolaos, et al.
Publicado: (2014)

Human Papillomavirus and Tonsillar and Base of Tongue Cancer
por: Ramqvist, Torbjörn, et al.
Publicado: (2015)

Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3
por: Bersani, Cinzia, et al.
Publicado: (2017)

Protein Expression in Tonsillar and Base of Tongue Cancer and in Relation to Human Papillomavirus (HPV) and Clinical Outcome
por: Ramqvist, Torbjörn, et al.
Publicado: (2018)

Tumor Infiltrating CD8(+) and Foxp3(+) Lymphocytes Correlate to Clinical Outcome and Human Papillomavirus (HPV) Status in Tonsillar Cancer
por: Näsman, Anders, et al.
Publicado: (2012)

Human Papillomavirus (HPV) 16 E6 Variants in Tonsillar Cancer in Comparison to Those in Cervical Cancer in Stockholm, Sweden
por: Du, Juan, et al.
Publicado: (2012)

Time to change perspectives on HPV in oropharyngeal cancer. A systematic review of HPV prevalence per oropharyngeal sub-site the last 3 years
por: Haeggblom, Linnea, et al.
Publicado: (2017)

Differences in gene expression between high‐grade dysplasia and invasive HPV(+) and HPV(−) tonsillar and base of tongue cancer
por: Haeggblom, Linnea, et al.
Publicado: (2019)

Absent/weak CD44 intensity and positive human papillomavirus (HPV) status in oropharyngeal squamous cell carcinoma indicates a very high survival
por: Näsman, Anders, et al.
Publicado: (2013)

Psoriasin expression is associated with survival in patients with human papillomavirus-positive base of tongue squamous cell carcinoma
por: Zupancic, Mark, et al.
Publicado: (2021)

Human papillomavirus and p53 expression in cancer of unknown primary in the head and neck region in relation to clinical outcome
por: Sivars, Lars, et al.
Publicado: (2014)

Prevalence of human papillomavirus and survival in oropharyngeal cancer other than tonsil or base of tongue cancer
por: Marklund, Linda, et al.
Publicado: (2012)

Human papillomavirus and survival of patients per histological subsite of tonsillar squamous cell carcinoma
por: Haeggblom, Linnea, et al.
Publicado: (2018)

Co-Inhibition of the Immunoproteasome Subunits LMP2 and LMP7 Ameliorates Immune Thrombocytopenia
por: Du, Sheng-hong, et al.
Publicado: (2021)

Immunohistochemical Identification and Assessment of the Location of Immunoproteasome Subunits LMP2 and LMP7 in Acquired Cholesteatoma
por: Rutkowska, Justyna, et al.
Publicado: (2023)

Association of LMP/TAP Gene Polymorphisms with Tuberculosis Susceptibility in Li Population in China
por: Wang, Danmei, et al.
Publicado: (2012)

Prevalence of Oral Human Papillomavirus Infection among Youth, Sweden
por: Du, Juan, et al.
Publicado: (2012)

Whole-Exome Sequencing of HPV Positive Tonsillar and Base of Tongue Squamous Cell Carcinomas Reveals a Global Mutational Pattern along with Relapse-Specific Somatic Variants
por: Ährlund-Richter, Andreas, et al.
Publicado: (2021)

The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis
por: French, Timothy, et al.
Publicado: (2021)

Prognostic Markers and Driver Genes and Options for Targeted Therapy in Human-Papillomavirus-Positive Tonsillar and Base-of-Tongue Squamous Cell Carcinoma
por: Näsman, Anders, et al.
Publicado: (2021)

Post-Treatment Neck Dissection of Tonsillar and Base of Tongue Squamous Cell Carcinoma in the Era of PET-CT, HPV, and p16
por: Landin, David, et al.
Publicado: (2022)

Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter
Publicado: (1995)

Transcriptome Changes Induced by Epstein-Barr Virus LMP1 and LMP2A in Transgenic Lymphocytes and Lymphoma
por: Shair, Kathy H. Y., et al.
Publicado: (2012)

The association between the genetic polymorphisms of LMP2/LMP7 and the outcomes of HCV infection among drug users()
por: Cui, Qian, et al.
Publicado: (2010)

HLA Class I and II Expression in Oropharyngeal Squamous Cell Carcinoma in Relation to Tumor HPV Status and Clinical Outcome
por: Näsman, Anders, et al.
Publicado: (2013)

LMP1 and LMP2A are potential prognostic markers of extranodal NK/T-cell lymphoma, nasal type (ENKTL)
por: Mao, Yuan, et al.
Publicado: (2012)

Molecular Screening of Nasopharyngeal Carcinoma: Detection of LMP-1, LMP-2 Gene Expression in Vietnamese Nasopharyngeal Swab Samples
por: Lao, Thuan Duc, et al.
Publicado: (2019)

Constructing TC-1-GLUC-LMP2 Model Tumor Cells to Evaluate the Anti-Tumor Effects of LMP2-Related Vaccines
por: Sun, Liying, et al.
Publicado: (2018)

The genetic association between LMP2 and LMP7 polymorphisms and susceptibility of insulin dependent diabetes mellitus: A meta-analysis
por: Xu, Yang, et al.
Publicado: (2020)

Novel Bifunctional Affibody Molecules with Specific Binding to Both EBV LMP1 and LMP2 for Targeted Therapy of Nasopharyngeal Carcinoma
por: Kamara, Saidu, et al.
Publicado: (2023)

Targeted Therapy With PI3K and FGFR Inhibitors on Human Papillomavirus Positive and Negative Tonsillar and Base of Tongue Cancer Lines With and Without Corresponding Mutations
por: Holzhauser, Stefan, et al.
Publicado: (2021)

The EBV-encoded Latent Membrane Proteins, LMP2A and LMP2B, Limit the Actions of Interferon by Targeting Interferon Receptors for Degradation
por: Shah, Khilan M., et al.
Publicado: (2009)

Genetic variability in LMP2 and LMP7 is associated with the risk of esophageal squamous cell carcinoma in the Kazakh population but is not associated with HPV infection
por: Yang, Lan, et al.
Publicado: (2017)

Epstein-Barr Virus LMP2A Reduces Hyperactivation Induced by LMP1 to Restore Normal B Cell Phenotype in Transgenic Mice
por: Vrazo, Alexandra C., et al.
Publicado: (2012)

Association between LMP2/LMP7 genetic variability and cancer susceptibility, especially among Asians: evidence from a meta-analysis
por: Wu, Yang, et al.
Publicado: (2017)

LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer
por: Cheng, Zhengyan, et al.
Publicado: (2023)

Changes in Cervical Human Papillomavirus (HPV) Prevalence at a Youth Clinic in Stockholm, Sweden, a Decade After the Introduction of the HPV Vaccine
por: Ährlund-Richter, Andreas, et al.
Publicado: (2019)

Measurement of CD8(+) and CD4(+) T Cell Frequencies Specific for EBV LMP1 and LMP2a Using mRNA-Transfected DCs
por: Sohn, Dae-Hee, et al.
Publicado: (2015)

Long-term Outcome of Extranodal NK/T Cell Lymphoma Patients Treated With Postremission Therapy Using EBV LMP1 and LMP2a-specific CTLs
por: Cho, Seok-Goo, et al.
Publicado: (2015)

Generating CTLs against the subdominant EBV LMP antigens by transit expression of an A20 inhibitor with EBV LMP proteins in human DCs
por: Hong, Bangxing, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_hf8tcp47vld3s8c5ba67llsmtr