Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl­amino]­meth­yl}cyclo­hexa­necarb­oxy­lic acid

The title compound, C(18)H(21)NO(4)S, is a new sulfonamide derivative of tranexamic acid. In the crystal, mol­ecules form inversion dimers via O—H⋯O hydrogen bonds involving the carb­oxy­lic acid groups. Hydrogen bonding between the sulfonamide N—H group and the carb­oxy­lic acid O atom assembles th...

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Autores principales: Danish, Muhammad, Tahir, Muhammad Nawaz, Hussain, Asif, Ashfaq, Muhammad, Sadiq, Muhammad Nadeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Data Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350692/
https://www.ncbi.nlm.nih.gov/pubmed/25844218
http://dx.doi.org/10.1107/S2056989015002054
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author Danish, Muhammad
Tahir, Muhammad Nawaz
Hussain, Asif
Ashfaq, Muhammad
Sadiq, Muhammad Nadeem
author_facet Danish, Muhammad
Tahir, Muhammad Nawaz
Hussain, Asif
Ashfaq, Muhammad
Sadiq, Muhammad Nadeem
author_sort Danish, Muhammad
collection PubMed
description The title compound, C(18)H(21)NO(4)S, is a new sulfonamide derivative of tranexamic acid. In the crystal, mol­ecules form inversion dimers via O—H⋯O hydrogen bonds involving the carb­oxy­lic acid groups. Hydrogen bonding between the sulfonamide N—H group and the carb­oxy­lic acid O atom assembles the dimers into thick layers parallel to (100). The naphthalene groups of adjacent layers are arranged in a herring-bone motif. There are C—H⋯π inter­actions between the naphthalene rings of neighbouring layers.
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spelling pubmed-43506922015-04-03 Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl­amino]­meth­yl}cyclo­hexa­necarb­oxy­lic acid Danish, Muhammad Tahir, Muhammad Nawaz Hussain, Asif Ashfaq, Muhammad Sadiq, Muhammad Nadeem Acta Crystallogr E Crystallogr Commun Data Reports The title compound, C(18)H(21)NO(4)S, is a new sulfonamide derivative of tranexamic acid. In the crystal, mol­ecules form inversion dimers via O—H⋯O hydrogen bonds involving the carb­oxy­lic acid groups. Hydrogen bonding between the sulfonamide N—H group and the carb­oxy­lic acid O atom assembles the dimers into thick layers parallel to (100). The naphthalene groups of adjacent layers are arranged in a herring-bone motif. There are C—H⋯π inter­actions between the naphthalene rings of neighbouring layers. International Union of Crystallography 2015-02-04 /pmc/articles/PMC4350692/ /pubmed/25844218 http://dx.doi.org/10.1107/S2056989015002054 Text en © Danish et al. 2015 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Data Reports
Danish, Muhammad
Tahir, Muhammad Nawaz
Hussain, Asif
Ashfaq, Muhammad
Sadiq, Muhammad Nadeem
Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl­amino]­meth­yl}cyclo­hexa­necarb­oxy­lic acid
title Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl­amino]­meth­yl}cyclo­hexa­necarb­oxy­lic acid
title_full Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl­amino]­meth­yl}cyclo­hexa­necarb­oxy­lic acid
title_fullStr Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl­amino]­meth­yl}cyclo­hexa­necarb­oxy­lic acid
title_full_unstemmed Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl­amino]­meth­yl}cyclo­hexa­necarb­oxy­lic acid
title_short Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl­amino]­meth­yl}cyclo­hexa­necarb­oxy­lic acid
title_sort crystal structure of 4-{[(naphthalen-2-yl)sulfonyl­amino]­meth­yl}cyclo­hexa­necarb­oxy­lic acid
topic Data Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350692/
https://www.ncbi.nlm.nih.gov/pubmed/25844218
http://dx.doi.org/10.1107/S2056989015002054
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