Crystal structure of (3S)-3-acet­oxy-17-(pyridin-3-yl)androsta-5,16-diene

In the title compound, C(26)H(33)NO(2) [systematic name: (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodeca­hydro-1H-cyclo­penta­[a]phenanthren-3-yl acetate], the steroid A, B, C and D rings adopt chair, half-chair, chair and envelope conformations, respecti...

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Detalles Bibliográficos
Autores principales: Zhou, Shengjun, Huang, Huaqi, Huang, Rongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Data Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350699/
https://www.ncbi.nlm.nih.gov/pubmed/25844219
http://dx.doi.org/10.1107/S2056989015001966
Descripción
Sumario:In the title compound, C(26)H(33)NO(2) [systematic name: (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodeca­hydro-1H-cyclo­penta­[a]phenanthren-3-yl acetate], the steroid A, B, C and D rings adopt chair, half-chair, chair and envelope conformations, respectively. The flap atom of the envelope is the methine C atom fused with the C ring. In the crystal, adjacent mol­ecules, generated by a 2(1) screw axis, are linked by weak C—H⋯O hydrogen bonds, forming a C(16) helical chain running along the c-axis direction.

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