Cargando…

Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-N-methoxy-N-methylpropanamide (Fernholz Weinreb amide)

The literature compound 3β-hydroxy-bisnor-5-cholenic aldehyde is an important intermediate for the synthesis of new modulators of the nuclear oxysterol receptor Liver X. As part of our ongoing search for new LXR antagonists, the title compound, C(24)H(39)NO(3), has proven to be an important inter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Viktorsson, Elvar Ørn, Åstrand, Ove Alexander Høgmoen, Haseeb, Rasha Sabah, Görbitz, Carl Henrik, Rongved, Pål
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2015
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350737/ https://www.ncbi.nlm.nih.gov/pubmed/25844186 http://dx.doi.org/10.1107/S2056989015001747

Ejemplares similares

17-(5-Ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol from Chisocheton tomentosus (Meliaceae)
por: Najmuldeen, Ibrahim A., et al.
Publicado: (2008)

10,13-Dimethyl-16-oxo-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
por: Shi, Rui, et al.
Publicado: (2010)

2-Methyl-6-(4,4,10,13,14-pentamethyl-3-oxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)hept-2-enoic acid
por: Arfan, Mohammad, et al.
Publicado: (2011)

2-(4-Bromophenyl)-2-methylpropanamide
por: Wang, Jian, et al.
Publicado: (2010)

β-Amino functionalization of cinnamic Weinreb amides in ionic liquid
por: Wang, Yi-Ning, et al.
Publicado: (2016)

[2,3,7,8,13,14,17,18-Octakis(ethylsulfanyl)-5,10,15,20-porphyrazinato]zinc(II)
por: Akkurt, Mehmet, et al.
Publicado: (2010)

Weinreb Amides as Directing Groups for Transition Metal-Catalyzed C-H Functionalizations
por: Kalepu, Jagadeesh, et al.
Publicado: (2019)

Methyl 11,14,16-triphenyl-8,12-dioxa-14,15-diazatetracyclo[8.7.0.0(2,7).0(13,17)]heptadeca-2(7),3,5,13(17),15-pentaene-10-carboxylate
por: Kanchanadevi, J., et al.
Publicado: (2013)

10,21-Dimethyl-2,7,13,18-tetraphenyl-3,6,14,17-tetraazatricyclo[17.3.1.1(8,12)]tetracosa-1(23),2,6,8(24),9,11,13,17,19,21-decaene-23,24-diol cyclohexane 0.33-solvate
por: Asatkar, Ashish K., et al.
Publicado: (2011)

Crystal structure of 16-hydroxy-4,4,10,13,14-pentamethyl-17-(6-methylhept-5-en-2-yl)-4,5,6,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
por: Ge, Jun-Jun, et al.
Publicado: (2015)

Prenatal Diagnosis of 17p13.1p13.3 Duplication
por: Kiiski, Kirsi, et al.
Publicado: (2012)

anti-2,2,3,3,6,6,7,7,10,10,11,11,14,14,15,15-Hexadecamethyl-2,3,6,7,10,11,14,15-octasilapentacyclo[10.4.2.2(4,9).0(5,8).0(13,16)]icosa-1(17),4,8,12(18),13(16),19-hexaene
por: Toma, Yuki, et al.
Publicado: (2013)

(1′S,12′R,13′S,17′S)-15′,15′-Dimethyl-1,2-dihydro-11′,14′,16′,18′-tetraoxa-7′-azaspiro[indole-3,8′-pentacyclo[10.6.0.0(2,9).0(3,7).0(13,17)]octadecane]-2,10′-dione
por: Sabari, V., et al.
Publicado: (2013)

Dichlorido[μ-10,21-dimethyl-2,7,13,18-tetraphenyl-3,6,14,17-tetraazatricyclo[17.3.1.1(8,12)]tetracosa-1(23),2,6,8,10,12(24),13,17,19,21-decaene-23,24-diolato]dicopper(II) ethanol hemisolvate dihydrate
por: Gupta, Sushil K., et al.
Publicado: (2010)

Memorandum: report on the 105 MeV/c LEAR run -14/10-17/10 - 22/10-31/10
por: CERN. Geneva. Proton Synchrotron and Synchrocyclotron Committee
Publicado: (1988)

Remote Radical 1,3-, 1,4-, 1,5-, 1,6- and 1,7-Difunctionalization Reactions †
por: Ma, Xiaoming, et al.
Publicado: (2023)

16-Methyl-11-(2-methylphenyl)-14-phenyl-8,12-dioxa-14,15-diazatetracyclo[8.7.0.0(2,7).0(13,17)]heptadeca-2(7),3,5,13(17),15-pentaene-10-carbonitrile
por: Kanchanadevi, Jeevanandam, et al.
Publicado: (2013)

(1R,2R,5R,6R,9S,10S,13S,14S)-1,6,7,8,9,14,15,16,17,17-Decachloropentacyclo[12.2.1.1(6,9).0(2,13).0(5,10)]octadeca-7,15-diene
por: Riddell, Nicole, et al.
Publicado: (2008)

Various endocrine disorders in children with t(13;14)(q10;q10) Robertsonian translocation
por: Choi, Byung Ho, et al.
Publicado: (2013)

3,6,14,17-Tetramethoxy-22,23-diphenyl-1,10,12,21-tetraazahexacyclo[19.2.1.0(2,7).0(10,23).0(12,22).0(13,18)]tetracosa-2(7),3,5,13(18),14,16-hexaene-11,24-dithione
por: Yang, Yan
Publicado: (2010)

Compte rendu du MD du 14 au 17.10.1986
Publicado: (1986)

Weinreb Amidation as the Cornerstone of an Improved Synthetic Route to A-Ring-Modified Derivatives of Luotonin A
por: Haider, Norbert, et al.
Publicado: (2012)

8,15-Dioxa-10,13-diazatetracyclo[14.4.0.0(2,7).0(9,14)]icosa-1(16),2,4,6,9(14),10,12,17,19-nonaene
por: Srinivasan, Thothadri, et al.
Publicado: (2013)

3-Iodo-8β,9α,14α-estra-1,3,5(10)-trien-17-one
por: Ketuly, Kamal Aziz, et al.
Publicado: (2009)

Towards STXS 1.3 (20'+10')
por: Bonanomi, Matteo
Publicado: (2022)

10(th) European Congress of Trauma and Emergency Surgery: May 13–17, 2009 Antalya, Turkey
Publicado: (2009)

[μ-10,21-Dimethyl-3,6,14,17-tetrazatricyclo[17.3.1.1(8,12)]tetracosa-1(23),2,6,8,10,12 (24),13,17,19,21-decaene-23,24-diolato-κ(4) N (3),N (6),O (23),O (24):κ(4) N (14),N (17),O (23),O (24)]bis(perchlorato-κO)dimanganese(II)
por: Liu, Jing, et al.
Publicado: (2008)

5,7,8,10,11,13,14,16-Octahydro-6,15-(ethanoxyethanoxyethano)-1,4:17,20-dietheno[9,12,6,15]benzodioxadiazacyclodocosine
por: Barnett, Heath A., et al.
Publicado: (2012)

(1R,2R,5R,6S,9R,10S,13S,14S,18R)-1,6,7,8,9,14,15,16,17,17,18-Undecachloropentacyclo[12.2.1.1(6,9).0(2,13).0(5,10)]octadeca-7,15-diene
por: Riddell, Nicole, et al.
Publicado: (2008)

Congenital hyperinsulinism and Poland syndrome in association with 10p13–14 duplication
por: Giri, Dinesh, et al.
Publicado: (2017)

11-[(E)-Benzylidene]-14-hydroxy-8-phenyl-3,13-diazaheptacyclo[13.7.1.1(9,13).0(2,9).0(2,14).0(3,7).0(19,23)]tetracosa-1(22),15,17,19(23),20-pentaen-10-one
por: Kumar, Raju Suresh, et al.
Publicado: (2010)

MPS STATUS REPORT No. 235 Period 17.2.1975-27.3.1975 (Weeks 8-9-10-11-12-13)
por: Asboe-Hansen, P
Publicado: (1974)

(1S,3R)-N-{(3S,10S,12S,13R,17R)-12-Hydroxy-17-[(R)-5-hydroxypentan-2-yl]-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl}adamantane-1-carboxamide 0.25-hydrate
por: Campos Fernandez, Cristian, et al.
Publicado: (2022)

10th Workshop on Electronics for LHC and Future Experiments: Boston, MA, USA 13 - 17 Sep 2004
por: Claude, Sandra
Publicado: (2004)

N,N′-(Propane-1,3-diyl)dibenzothioamide
por: Nagasawa, Masayuki, et al.
Publicado: (2014)

3,7,10,14,15-pentaacetyl-5-butanoyl-13,17-epoxy-8-myrsinene a novel compound isolated from Pycnocycla spinosa extract with potent anti-spasmodic and antidiarrheal properties
por: Sadraei, H., et al.
Publicado: (2015)

(Z)-3α-(1,3-Dioxoisoindolin-2-yl)-17(20)-pregnene
por: Qi, Yue, et al.
Publicado: (2011)

Synthesis, Biological Evaluation and Docking Studies of 13-Epimeric 10-fluoro- and 10-Chloroestra-1,4-dien-3-ones as Potential Aromatase Inhibitors
por: Jójárt, Rebeka, et al.
Publicado: (2019)

17α-Ethynyl-3-methoxyestra-1,3,5(10),9(11)-tetraen-17-ol
por: Li, Hongqi, et al.
Publicado: (2008)

(8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-diene
por: Ketuly, Kamal Aziz, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_8o9as5uhghbhrkfvl85tenrdi2