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The Inhibitory Effect of Kakkonto, Japanese Traditional (Kampo) Medicine, on Brain Penetration of Oseltamivir Carboxylate in Mice with Reduced Blood-Brain Barrier Function

Oseltamivir phosphate (OP) is used to treat influenza virus infections. However, its use may result in central nervous system (CNS) adverse effects. In Japan, OP is used with Kampo formulations to improve clinical effectiveness. We evaluated the potential for using Kampo formulations to reduce CNS a...

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Detalles Bibliográficos
Autores principales:	Ohara, Kousuke, Oshima, Shinji, Fukuda, Nanami, Ochiai, Yumiko, Maruyama, Ayumi, Kanamuro, Aki, Negishi, Akio, Honma, Seiichi, Ohshima, Shigeru, Akimoto, Masayuki, Takenaka, Shingo, Kobayashi, Daisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350872/ https://www.ncbi.nlm.nih.gov/pubmed/25788966 http://dx.doi.org/10.1155/2015/917670

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