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Distinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma

BACKGROUND: The mechanistic target of rapamycin, (mTOR) kinase plays a pivotal role in controlling critical cellular growth and survival pathways, and its aberrant induction is implicated in cancer pathogenesis. Therefore, suppression of active mTOR signaling has been of great interest to researcher...

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Detalles Bibliográficos
Autores principales:	Mazan-Mamczarz, Krystyna, Peroutka, Raymond J, Steinhardt, James J, Gidoni, Moriah, Zhang, Yongqing, Lehrmann, Elin, Landon, Ari L, Dai, Bojie, Houng, Simone, Muniandy, Parameswary A, Efroni, Sol, Becker, Kevin G, Gartenhaus, Ronald B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350884/ https://www.ncbi.nlm.nih.gov/pubmed/25849580 http://dx.doi.org/10.1186/s12964-015-0091-0

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