Cargando…
Role of information in preparing men for transrectal ultrasound guided prostate biopsy: a qualitative study embedded in the ProtecT trial
BACKGROUND: The histological diagnosis of prostate cancer requires a prostate needle biopsy. Little is known about the relationship between information provided to prepare men for transrectal ultrasound guided biopsy (TRUS-Bx) and how men experience biopsy. The objectives were a) to understand men’s...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350900/ https://www.ncbi.nlm.nih.gov/pubmed/25889315 http://dx.doi.org/10.1186/s12913-015-0729-z |
_version_ | 1782360251472805888 |
---|---|
author | Wade, Julia Rosario, Derek J Howson, Joanne Avery, Kerry N L Salter, C Elizabeth Goodwin, M Louise Blazeby, Jane M Lane, J Athene Metcalfe, Chris Neal, David E Hamdy, Freddie C Donovan, Jenny L |
author_facet | Wade, Julia Rosario, Derek J Howson, Joanne Avery, Kerry N L Salter, C Elizabeth Goodwin, M Louise Blazeby, Jane M Lane, J Athene Metcalfe, Chris Neal, David E Hamdy, Freddie C Donovan, Jenny L |
author_sort | Wade, Julia |
collection | PubMed |
description | BACKGROUND: The histological diagnosis of prostate cancer requires a prostate needle biopsy. Little is known about the relationship between information provided to prepare men for transrectal ultrasound guided biopsy (TRUS-Bx) and how men experience biopsy. The objectives were a) to understand men’s experiences of biopsy as compared to their expectations; and b) to propose current evidence-based information for men undergoing TRUS-Bx. METHODS: Between February 2006 and May 2008, 1,147 men undergoing a standardised 10-core transrectal ultrasound guided biopsy protocol under antibiotic cover following a PSA 3.0-19.9 ng/ml in the Prostate Testing for Cancer and Treatment (ProtecT) trial, completed questionnaires about biopsy symptoms. In this embedded qualitative study, in-depth interviews were undertaken with 85 men (mean age 63.6 yrs, mean PSA 4.5 ng/ml) to explore men’s experiences of prostate biopsy and how the experience might be improved. Interview data were analysed thematically using qualitative research methods. Findings from the qualitative study were used to guide selection of key findings from the questionnaire study in developing a patient information leaflet preparing men for biopsy. RESULTS: Although most men tolerated TRUS-Bx, a quarter reported problematic side-effects and anxiety. Side effects were perceived as problematic and anxiety arose most commonly when experiences deviated from information provided. Men who were unprepared for elements of TRUS-Bx procedure or its sequelae responded by contacting health professionals for reassurance and voiced frustration that pre-biopsy information had understated the possible severity or duration of pain/discomfort and bleeding. Findings from questionnaire and interview data were combined to propose a comprehensive, evidence-based patient information leaflet for TRUS-Bx. CONCLUSIONS: Men reported anxiety associated with TRUS-Bx or its side-effects most commonly if they felt inadequately prepared for the procedure. Data from this qualitative study and the previous questionnaire study have been used to propose an updated, comprehensive evidence-based set of information for men undergoing TRUS-Bx. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12913-015-0729-z) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4350900 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-43509002015-03-06 Role of information in preparing men for transrectal ultrasound guided prostate biopsy: a qualitative study embedded in the ProtecT trial Wade, Julia Rosario, Derek J Howson, Joanne Avery, Kerry N L Salter, C Elizabeth Goodwin, M Louise Blazeby, Jane M Lane, J Athene Metcalfe, Chris Neal, David E Hamdy, Freddie C Donovan, Jenny L BMC Health Serv Res Research Article BACKGROUND: The histological diagnosis of prostate cancer requires a prostate needle biopsy. Little is known about the relationship between information provided to prepare men for transrectal ultrasound guided biopsy (TRUS-Bx) and how men experience biopsy. The objectives were a) to understand men’s experiences of biopsy as compared to their expectations; and b) to propose current evidence-based information for men undergoing TRUS-Bx. METHODS: Between February 2006 and May 2008, 1,147 men undergoing a standardised 10-core transrectal ultrasound guided biopsy protocol under antibiotic cover following a PSA 3.0-19.9 ng/ml in the Prostate Testing for Cancer and Treatment (ProtecT) trial, completed questionnaires about biopsy symptoms. In this embedded qualitative study, in-depth interviews were undertaken with 85 men (mean age 63.6 yrs, mean PSA 4.5 ng/ml) to explore men’s experiences of prostate biopsy and how the experience might be improved. Interview data were analysed thematically using qualitative research methods. Findings from the qualitative study were used to guide selection of key findings from the questionnaire study in developing a patient information leaflet preparing men for biopsy. RESULTS: Although most men tolerated TRUS-Bx, a quarter reported problematic side-effects and anxiety. Side effects were perceived as problematic and anxiety arose most commonly when experiences deviated from information provided. Men who were unprepared for elements of TRUS-Bx procedure or its sequelae responded by contacting health professionals for reassurance and voiced frustration that pre-biopsy information had understated the possible severity or duration of pain/discomfort and bleeding. Findings from questionnaire and interview data were combined to propose a comprehensive, evidence-based patient information leaflet for TRUS-Bx. CONCLUSIONS: Men reported anxiety associated with TRUS-Bx or its side-effects most commonly if they felt inadequately prepared for the procedure. Data from this qualitative study and the previous questionnaire study have been used to propose an updated, comprehensive evidence-based set of information for men undergoing TRUS-Bx. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12913-015-0729-z) contains supplementary material, which is available to authorized users. BioMed Central 2015-02-28 /pmc/articles/PMC4350900/ /pubmed/25889315 http://dx.doi.org/10.1186/s12913-015-0729-z Text en © Wade et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Wade, Julia Rosario, Derek J Howson, Joanne Avery, Kerry N L Salter, C Elizabeth Goodwin, M Louise Blazeby, Jane M Lane, J Athene Metcalfe, Chris Neal, David E Hamdy, Freddie C Donovan, Jenny L Role of information in preparing men for transrectal ultrasound guided prostate biopsy: a qualitative study embedded in the ProtecT trial |
title | Role of information in preparing men for transrectal ultrasound guided prostate biopsy: a qualitative study embedded in the ProtecT trial |
title_full | Role of information in preparing men for transrectal ultrasound guided prostate biopsy: a qualitative study embedded in the ProtecT trial |
title_fullStr | Role of information in preparing men for transrectal ultrasound guided prostate biopsy: a qualitative study embedded in the ProtecT trial |
title_full_unstemmed | Role of information in preparing men for transrectal ultrasound guided prostate biopsy: a qualitative study embedded in the ProtecT trial |
title_short | Role of information in preparing men for transrectal ultrasound guided prostate biopsy: a qualitative study embedded in the ProtecT trial |
title_sort | role of information in preparing men for transrectal ultrasound guided prostate biopsy: a qualitative study embedded in the protect trial |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350900/ https://www.ncbi.nlm.nih.gov/pubmed/25889315 http://dx.doi.org/10.1186/s12913-015-0729-z |
work_keys_str_mv | AT wadejulia roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT rosarioderekj roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT howsonjoanne roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT averykerrynl roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT saltercelizabeth roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT goodwinmlouise roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT blazebyjanem roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT lanejathene roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT metcalfechris roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT nealdavide roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT hamdyfreddiec roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial AT donovanjennyl roleofinformationinpreparingmenfortransrectalultrasoundguidedprostatebiopsyaqualitativestudyembeddedintheprotecttrial |