A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation

Toxic megacolon is a rare clinical complication of fulminant Clostridium difficile infection. The mortality rate of fulminant C. difficile infection is reported to be as high as 50%. Fecal microbiota transplantation is a highly effective treatment in patients with recurrent or refractory C. difficil...

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Detalles Bibliográficos
Autores principales: Gweon, Tae-Geun, Lee, Kyung Jin, Kang, Donghoon, Park, Sung Soo, Kim, Kyung Hoon, Seong, Hyeonjin, Ban, Tae-Hyun, Moon, Sung Jin, Kim, Jin Su, Kim, Sang Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gut and Liver 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351033/
https://www.ncbi.nlm.nih.gov/pubmed/25721003
http://dx.doi.org/10.5009/gnl14152
Descripción
Sumario:Toxic megacolon is a rare clinical complication of fulminant Clostridium difficile infection. The mortality rate of fulminant C. difficile infection is reported to be as high as 50%. Fecal microbiota transplantation is a highly effective treatment in patients with recurrent or refractory C. difficile infection. However, there are few published articles on the use of such transplantation for fulminant C. difficile infection. Here, we report on a patient with toxic megacolon complicated by C. difficile infection who was treated successfully with fecal microbiota transplantation.

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