A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation

Toxic megacolon is a rare clinical complication of fulminant Clostridium difficile infection. The mortality rate of fulminant C. difficile infection is reported to be as high as 50%. Fecal microbiota transplantation is a highly effective treatment in patients with recurrent or refractory C. difficil...

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Autores principales: Gweon, Tae-Geun, Lee, Kyung Jin, Kang, Donghoon, Park, Sung Soo, Kim, Kyung Hoon, Seong, Hyeonjin, Ban, Tae-Hyun, Moon, Sung Jin, Kim, Jin Su, Kim, Sang Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gut and Liver 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351033/
https://www.ncbi.nlm.nih.gov/pubmed/25721003
http://dx.doi.org/10.5009/gnl14152
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author Gweon, Tae-Geun
Lee, Kyung Jin
Kang, Donghoon
Park, Sung Soo
Kim, Kyung Hoon
Seong, Hyeonjin
Ban, Tae-Hyun
Moon, Sung Jin
Kim, Jin Su
Kim, Sang Woo
author_facet Gweon, Tae-Geun
Lee, Kyung Jin
Kang, Donghoon
Park, Sung Soo
Kim, Kyung Hoon
Seong, Hyeonjin
Ban, Tae-Hyun
Moon, Sung Jin
Kim, Jin Su
Kim, Sang Woo
author_sort Gweon, Tae-Geun
collection PubMed
description Toxic megacolon is a rare clinical complication of fulminant Clostridium difficile infection. The mortality rate of fulminant C. difficile infection is reported to be as high as 50%. Fecal microbiota transplantation is a highly effective treatment in patients with recurrent or refractory C. difficile infection. However, there are few published articles on the use of such transplantation for fulminant C. difficile infection. Here, we report on a patient with toxic megacolon complicated by C. difficile infection who was treated successfully with fecal microbiota transplantation.
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spelling pubmed-43510332015-03-12 A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation Gweon, Tae-Geun Lee, Kyung Jin Kang, Donghoon Park, Sung Soo Kim, Kyung Hoon Seong, Hyeonjin Ban, Tae-Hyun Moon, Sung Jin Kim, Jin Su Kim, Sang Woo Gut Liver Case Report Toxic megacolon is a rare clinical complication of fulminant Clostridium difficile infection. The mortality rate of fulminant C. difficile infection is reported to be as high as 50%. Fecal microbiota transplantation is a highly effective treatment in patients with recurrent or refractory C. difficile infection. However, there are few published articles on the use of such transplantation for fulminant C. difficile infection. Here, we report on a patient with toxic megacolon complicated by C. difficile infection who was treated successfully with fecal microbiota transplantation. Gut and Liver 2015-03 2015-03-15 /pmc/articles/PMC4351033/ /pubmed/25721003 http://dx.doi.org/10.5009/gnl14152 Text en Copyright © 2015 by The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association for the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gweon, Tae-Geun
Lee, Kyung Jin
Kang, Donghoon
Park, Sung Soo
Kim, Kyung Hoon
Seong, Hyeonjin
Ban, Tae-Hyun
Moon, Sung Jin
Kim, Jin Su
Kim, Sang Woo
A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation
title A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation
title_full A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation
title_fullStr A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation
title_full_unstemmed A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation
title_short A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation
title_sort case of toxic megacolon caused by clostridium difficile infection and treated with fecal microbiota transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351033/
https://www.ncbi.nlm.nih.gov/pubmed/25721003
http://dx.doi.org/10.5009/gnl14152
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