Cargando…

Protein Topology Determines Cysteine Oxidation Fate: The Case of Sulfenyl Amide Formation among Protein Families

Cysteine residues have a rich chemistry and play a critical role in the catalytic activity of a plethora of enzymes. However, cysteines are susceptible to oxidation by Reactive Oxygen and Nitrogen Species, leading to a loss of their catalytic function. Therefore, cysteine oxidation is emerging as a...

Descripción completa

Detalles Bibliográficos
Autores principales: Defelipe, Lucas A., Lanzarotti, Esteban, Gauto, Diego, Marti, Marcelo A., Turjanski, Adrián G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351059/
https://www.ncbi.nlm.nih.gov/pubmed/25741692
http://dx.doi.org/10.1371/journal.pcbi.1004051