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Lincosamide Synthetase—A Unique Condensation System Combining Elements of Nonribosomal Peptide Synthetase and Mycothiol Metabolism

In the biosynthesis of lincosamide antibiotics lincomycin and celesticetin, the amino acid and amino sugar units are linked by an amide bond. The respective condensing enzyme lincosamide synthetase (LS) is expected to be an unusual system combining nonribosomal peptide synthetase (NRPS) components w...

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Detalles Bibliográficos
Autores principales:	Janata, Jiri, Kadlcik, Stanislav, Koberska, Marketa, Ulanova, Dana, Kamenik, Zdenek, Novak, Petr, Kopecky, Jan, Novotna, Jitka, Radojevic, Bojana, Plhackova, Kamila, Gazak, Radek, Najmanova, Lucie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351081/ https://www.ncbi.nlm.nih.gov/pubmed/25741696 http://dx.doi.org/10.1371/journal.pone.0118850

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