Cargando…

Significant In Vivo Anti-Inflammatory Activity of Pytren4Q-Mn a Superoxide Dismutase 2 (SOD2) Mimetic Scorpiand-Like Mn (II) Complex

BACKGROUND: The clinical use of purified SOD enzymes has strong limitations due to their large molecular size, high production cost and immunogenicity. These limitations could be compensated by using instead synthetic SOD mimetic compounds of low molecular weight. BACKGROUND/METHODOLOGY: We have rec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Serena, Carolina, Calvo, Enrique, Clares, Mari Paz, Diaz, María Luisa, Chicote, Javier U., Beltrán-Debon, Raúl, Fontova, Ramón, Rodriguez, Alejandro, García-España, Enrique, García-España, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351122/ https://www.ncbi.nlm.nih.gov/pubmed/25742129 http://dx.doi.org/10.1371/journal.pone.0119102

Ejemplares similares

Superoxide Dismutases (SODs) and SOD Mimetics
por: Borgstahl, Gloria E. O., et al.
Publicado: (2018)

Ditopic Aza-Scorpiand Ligands Interact Selectively with ds-RNA and Modulate the Interaction upon Formation of Zn(2+) Complexes
por: Guijarro, Lluís, et al.
Publicado: (2021)

Small Molecule Pytren-4QMn Metal Complex Slows down Huntington’s Disease Progression in Male zQ175 Transgenic Mice
por: Merino, Marián, et al.
Publicado: (2023)

A step forward in the development of superoxide dismutase mimetic nanozymes: the effect of the charge of the surface on antioxidant activity
por: Martínez-Camarena, Álvaro, et al.
Publicado: (2019)

Immunohistochemical assessment of mitochondrial superoxide dismutase (MnSOD) in colorectal premalignant and malignant lesions
por: Piecuch, Adam, et al.
Publicado: (2016)

Molecular Rearrangement of an Aza-Scorpiand Macrocycle Induced by pH: A Computational Study †
por: De Julián-Ortiz, Jesus Vicente, et al.
Publicado: (2016)

Identification of Aryl Polyamines Derivatives as Anti-Trypanosoma cruzi Agents Targeting Iron Superoxide Dismutase †
por: Martín-Escolano, Rubén, et al.
Publicado: (2022)

Changes in the Activity and Concentration of Superoxide Dismutase Isoenzymes (Cu/Zn SOD, MnSOD) in the Blood of Healthy Subjects and Patients with Acute Pancreatitis
por: Ściskalska, Milena, et al.
Publicado: (2020)

Radioprotective and tumor antiangiogenic effect of the novel synthetic superoxide dismutase (SOD) mimetic compounds
por: Vujaskovic, Z, et al.
Publicado: (2001)

SODa: An Mn/Fe superoxide dismutase prediction and design server
por: Kwasigroch, Jean Marc, et al.
Publicado: (2008)

Orally available Mn porphyrins with superoxide dismutase and catalase activities
por: Rosenthal, Rosalind A., et al.
Publicado: (2009)

Additive Contributions of Two Manganese-Cored Superoxide Dismutases (MnSODs) to Antioxidation, UV Tolerance and Virulence of Beauveria bassiana
por: Xie, Xue-Qin, et al.
Publicado: (2012)

A Case-Control Study Exploring the Role of Serum Manganese Superoxide Dismutase (MnSOD) Levels in Gastric Cancer
por: Lin, Yingsong, et al.
Publicado: (2005)

Therapeutic Effects of the Superoxide Dismutase Mimetic Compound Mn(II)Me(2)DO2A on Experimental Articular Pain in Rats
por: Di Cesare Mannelli, Lorenzo, et al.
Publicado: (2013)

Mn(II) Quinoline Complex (4QMn) Restores Proteostasis and Reduces Toxicity in Experimental Models of Huntington’s Disease
por: Merino, Marián, et al.
Publicado: (2022)

A New Mixed-Valence Mn(II)Mn(III) Compound With Catalase and Superoxide Dismutase Activities
por: Costa, Rafael O., et al.
Publicado: (2018)

The Paradoxical Leishmanicidal Effects of Superoxide Dismutase (SOD)-Mimetic Tempol in Leishmania braziliensis Infection in vitro
por: Oliveira, Laíse B., et al.
Publicado: (2019)

Rational Design of Superoxide Dismutase (SOD) Mimics: The Evaluation of the Therapeutic Potential of New Cationic Mn Porphyrins with Linear and Cyclic Substituents
por: Tovmasyan, Artak, et al.
Publicado: (2014)

Experimental autoimmune encephalomyelitis (EAE) up-regulates the mitochondrial activity and manganese superoxide dismutase (MnSOD) in the mouse renal cortex
por: Packialakshmi, Balamurugan, et al.
Publicado: (2018)

Association of the Manganese Superoxide Dismutase (Mn-SOD) Gene C47T Polymorphism with Lung Cancer: A Case-Control Study
por: Hoidy, Wisam H, et al.
Publicado: (2022)

Characterization of ancestral Fe/Mn superoxide dismutases indicates their cambialistic origin
por: Valenti, Rosario, et al.
Publicado: (2022)

Manganese Superoxide Dismutase (MnSOD) expression is negatively associated with microRNA-301a in human Pancreatic Ductal Adenocarcinoma (PDAC)
por: Pandit, Harshul, et al.
Publicado: (2015)

Roles of the Two-MnSOD System of Stenotrophomonas maltophilia in the Alleviation of Superoxide Stress
por: Jair, Herng-Woei, et al.
Publicado: (2019)

An Electrophysiological and Proteomic Analysis of the Effects of the Superoxide Dismutase Mimetic, MnTMPyP, on Synaptic Signalling Post-Ischemia in Isolated Rat Hippocampal Slices
por: Puzio, Martina, et al.
Publicado: (2023)

Expression of Mn-Superoxide Dismutase Gene in Nontumorigenic and Tumorigenic Human Mammary Epithelial Cells
por: Mukhopadhyay, Sutapa, et al.
Publicado: (2004)

Paradoxical Relationship between Mn Superoxide Dismutase Deficiency and Radiation-Induced Cognitive Defects
por: Corniola, Rikki, et al.
Publicado: (2012)

A Study of the Activity of Recombinant Mn-Superoxide Dismutase in the Presence of Gold and Silver Nanoparticles
por: Pudlarz, Agnieszka Małgorzata, et al.
Publicado: (2018)

Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE
por: Filograna, Roberta, et al.
Publicado: (2016)

Superoxide Enhances the Antitumor Combination of AdMnSOD Plus BCNU in Breast Cancer
por: Sun, Wenqing G., et al.
Publicado: (2010)

MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management
por: Bellot, Gregory Lucien, et al.
Publicado: (2018)

Superoxide Dismutase Gene (SOD1, SOD2, and SOD3) Polymorphisms and Antituberculosis Drug-induced Hepatitis
por: Kim, Sang-Hoon, et al.
Publicado: (2015)

Modeling and analysis of soybean (Glycine max. L) Cu/Zn, Mn and Fe superoxide dismutases
por: Gopavajhula, V. Ramana, et al.
Publicado: (2013)

The activity of superoxide dismutases (SODs) at the early stages of wheat deetiolation
por: Leonowicz, Gracjana, et al.
Publicado: (2018)

Determination of superoxide dismutase mimetic activity in common culinary herbs
por: Chohan, Magali, et al.
Publicado: (2014)

Modulation of In Utero Total Body Irradiation Induced Newborn Mouse Growth Retardation by Maternal Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Gene Therapy
por: Epperly, Michael W., et al.
Publicado: (2011)

Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes
por: Coudriet, Gina M., et al.
Publicado: (2017)

Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans
por: Van Raamsdonk, Jeremy M., et al.
Publicado: (2009)

A lecithinized superoxide dismutase (PC-SOD) improves ulcerative colitis
por: Suzuki, Y, et al.
Publicado: (2008)

Human extracellular superoxide dismutase (EC-SOD) expression in transgenic chicken
por: Byun, Sung June, et al.
Publicado: (2013)

The Effect of Extracellular Superoxide Dismutase (SOD3) Gene in Lung Cancer
por: Zhang, Yundi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a1hngebmg43m3rb1r6snonetup