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Evolution and Phenotypic Selection of Cancer Stem Cells

Cells of different organs at different ages have an intrinsic set of kinetics that dictates their behavior. Transformation into cancer cells will inherit these kinetics that determine initial cell and tumor population progression dynamics. Subject to genetic mutation and epigenetic alterations, canc...

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Detalles Bibliográficos
Autores principales: Poleszczuk, Jan, Hahnfeldt, Philip, Enderling, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351192/
https://www.ncbi.nlm.nih.gov/pubmed/25742563
http://dx.doi.org/10.1371/journal.pcbi.1004025