Cargando…
Functional Aspects of Intrahepatic Hepatitis B Virus-specific T Cells Induced by Therapeutic DNA Vaccination
Current therapies for the hepatitis B virus (HBV), a major cause of severe liver disease, suppress viral replication but replication rebounds if therapy is withdrawn. It is widely accepted that immune activation is needed to control replication off-therapy. To specifically activate T cells crossreac...
Autores principales: | Brass, Anette, Frelin, Lars, Milich, David R, Sällberg, Matti, Ahlén, Gustaf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351461/ https://www.ncbi.nlm.nih.gov/pubmed/25492563 http://dx.doi.org/10.1038/mt.2014.233 |
Ejemplares similares
-
A Heterologous Prime/Boost Vaccination Strategy Enhances the Immunogenicity of Therapeutic Vaccines for Hepatitis C Virus
por: Fournillier, Anne, et al.
Publicado: (2013) -
Functional differences in hepatitis C virus nonstructural (NS) 3/4A- and 5A-specific T cell responses
por: Holmström, Fredrik, et al.
Publicado: (2016) -
Therapeutic DNA Vaccination Using In Vivo Electroporation Followed by Standard of Care Therapy in Patients With Genotype 1 Chronic Hepatitis C
por: Weiland, Ola, et al.
Publicado: (2013) -
Immune-mediated effects targeting hepatitis C virus in a syngeneic replicon cell transplantation mouse model
por: Levander, Sepideh, et al.
Publicado: (2018) -
A small step closer to the Holy Grail of DNA vaccines: undisputed clinical benefit in humans
por: Frelin, Lars, et al.
Publicado: (2009)