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Whole exome sequencing reveals recurrent mutations in BRCA2 and FAT genes in acinar cell carcinomas of the pancreas

Acinar cell carcinoma of the pancreas is a rare tumor with a poor prognosis. Compared to pancreatic ductal adenocarcinoma, its molecular features are poorly known. We studied a total of 11 acinar cell carcinomas, including 3 by exome and 4 by target sequencing. Exome sequencing revealed 65 nonsynony...

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Detalles Bibliográficos
Autores principales:	Furukawa, Toru, Sakamoto, Hitomi, Takeuchi, Shoko, Ameri, Mitra, Kuboki, Yuko, Yamamoto, Toshiyuki, Hatori, Takashi, Yamamoto, Masakazu, Sugiyama, Masanori, Ohike, Nobuyuki, Yamaguchi, Hiroshi, Shimizu, Michio, Shibata, Noriyuki, Shimizu, Kyoko, Shiratori, Keiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351513/ https://www.ncbi.nlm.nih.gov/pubmed/25743105 http://dx.doi.org/10.1038/srep08829

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