Cargando…
3D Pharmacophoric Similarity improves Multi Adverse Drug Event Identification in Pharmacovigilance
Adverse drugs events (ADEs) detection constitutes a considerable concern in patient safety and public health care. For this reason, it is important to develop methods that improve ADE signal detection in pharmacovigilance databases. Our objective is to apply 3D pharmacophoric similarity models to en...
Autores principales: | Vilar, Santiago, Tatonetti, Nicholas P., Hripcsak, George |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351525/ https://www.ncbi.nlm.nih.gov/pubmed/25744369 http://dx.doi.org/10.1038/srep08809 |
Ejemplares similares
-
Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling
por: Vilar, Santiago, et al.
Publicado: (2015) -
Leveraging 3D chemical similarity, target and phenotypic data in the identification of drug-protein and drug-adverse effect associations
por: Vilar, Santiago, et al.
Publicado: (2016) -
Similarity-Based Modeling Applied to Signal Detection in Pharmacovigilance
por: Vilar, S, et al.
Publicado: (2014) -
Systems pharmacology augments drug safety surveillance
por: Lorberbaum, Tal, et al.
Publicado: (2014) -
Pharmacovigilance and drug safety 2011 in Calabria (Italy): Adverse events analysis
por: Scicchitano, Francesca, et al.
Publicado: (2012)