Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci

The interplay between genetic and epigenetic variation is only partially understood. One form of epigenetic variation is methylation at CpG sites, which can be measured as methylation quantitative trait loci (meQTL). Here we report that in a panel of lymphocytes from 1,748 individuals, methylation l...

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Detalles Bibliográficos
Autores principales: Lemire, Mathieu, Zaidi, Syed H.E., Ban, Maria, Ge, Bing, Aïssi, Dylan, Germain, Marine, Kassam, Irfahan, Wang, Mike, Zanke, Brent W., Gagnon, France, Morange, Pierre-Emmanuel, Trégouët, David-Alexandre, Wells, Philip S., Sawcer, Stephen, Gallinger, Steven, Pastinen, Tomi, Hudson, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351585/
https://www.ncbi.nlm.nih.gov/pubmed/25716334
http://dx.doi.org/10.1038/ncomms7326

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