Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity

Predicting clinical response to anticancer drugs remains a major challenge in cancer treatment. Emerging reports indicate that the tumour microenvironment and heterogeneity can limit the predictive power of current biomarker-guided strategies for chemotherapy. Here we report the engineering of perso...

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Detalles Bibliográficos
Autores principales: Majumder, Biswanath, Baraneedharan, Ulaganathan, Thiyagarajan, Saravanan, Radhakrishnan, Padhma, Narasimhan, Harikrishna, Dhandapani, Muthu, Brijwani, Nilesh, Pinto, Dency D., Prasath, Arun, Shanthappa, Basavaraja U., Thayakumar, Allen, Surendran, Rajagopalan, Babu, Govind K., Shenoy, Ashok M., Kuriakose, Moni A., Bergthold, Guillaume, Horowitz, Peleg, Loda, Massimo, Beroukhim, Rameen, Agarwal, Shivani, Sengupta, Shiladitya, Sundaram, Mallikarjun, Majumder, Pradip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351621/
https://www.ncbi.nlm.nih.gov/pubmed/25721094
http://dx.doi.org/10.1038/ncomms7169

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