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Independent recruitment of Igh alleles in V(D)J recombination

How the vast majority of B cells express only one of the two alleles at their immunoglobulin loci remains a biological puzzle. Here, in mice reconstituted with a single haematopoietic stem cell, we demonstrate that each of the two immunoglobulin heavy chain (Igh) alleles has a similar probability to...

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Detalles Bibliográficos
Autores principales:	Alves-Pereira, Clara F., de Freitas, Raquel, Lopes, Telma, Gardner, Rui, Marta, Filipa, Vieira, Paulo, Barreto, Vasco M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351640/ https://www.ncbi.nlm.nih.gov/pubmed/25517887 http://dx.doi.org/10.1038/ncomms6623

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