OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer

BACKGROUND: OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a deubiquitinating enzyme (DUB) that belongs to the OTU (ovarian tumor) superfamily. The aim of this study was to clarify the role of OTUB1 in colorectal cancer (CRC) and to identify the mechanism underlying its function. METHOD...

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Detalles Bibliográficos
Autores principales: Zhou, Yi, Wu, Jiangxue, Fu, Xiang, Du, Wuying, Zhou, Ling, Meng, Xiangqi, Yu, Hongyan, Lin, Jiaxin, Ye, Wen, Liu, Jiani, Peng, Hui, Liu, Ran-yi, Pan, Changchuan, Huang, Wenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351937/
https://www.ncbi.nlm.nih.gov/pubmed/25431208
http://dx.doi.org/10.1186/1476-4598-13-258

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