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PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145
The human genome encodes a family of nine protein arginine methyltransferases (PRMT1-9), which members can catalyze three distinct types of methylation on arginine residues. Here, we identify two spliceosome-associated proteins – SAP145 and SAP49 – as PRMT9 binding partners, linking PRMT9 to U2snRNP...
Autores principales: | Yang, Yanzhong, Hadjikyriacou, Andrea, Xia, Zheng, Gayatri, Sitaram, Kim, Daehoon, Zurita-Lopez, Cecilia, Kelly, Ryan, Guo, Ailan, Li, Wei, Clarke, Steven G., Bedford, Mark T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351962/ https://www.ncbi.nlm.nih.gov/pubmed/25737013 http://dx.doi.org/10.1038/ncomms7428 |
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