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Pregnane X Receptor Knockout Mice Display Aging-Dependent Wearing of Articular Cartilage

Steroid and xenobiotic receptor (SXR) and its murine ortholog, pregnane X receptor (PXR), are nuclear receptors that are expressed at high levels in the liver and the intestine where they function as xenobiotic sensors that induce expression of genes involved in detoxification and drug excretion. Re...

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Detalles Bibliográficos
Autores principales:	Azuma, Kotaro, Casey, Stephanie C., Urano, Tomohiko, Horie-Inoue, Kuniko, Ouchi, Yasuyoshi, Blumberg, Bruce, Inoue, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352085/ https://www.ncbi.nlm.nih.gov/pubmed/25749104 http://dx.doi.org/10.1371/journal.pone.0119177

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