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Surgical aortic valve replacement in patients older than 75 years: is there really a quality of life benefit?

BACKGROUND: To evaluate the results of elective isolated surgical aortic valve replacement (SAVR) on quality of life (QoL) in patients > 75 years. METHODS: 138 patients operated between January 2008 and December 2011 were included. The EuroQOL questionnaire (EQ-5D, EQ-VAS) was completed preoperat...

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Autores principales: van Laar, Charlotte, Kievit, Peter C., Noyez, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bohn Stafleu van Loghum 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352151/
https://www.ncbi.nlm.nih.gov/pubmed/25884084
http://dx.doi.org/10.1007/s12471-015-0660-2
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author van Laar, Charlotte
Kievit, Peter C.
Noyez, Luc
author_facet van Laar, Charlotte
Kievit, Peter C.
Noyez, Luc
author_sort van Laar, Charlotte
collection PubMed
description BACKGROUND: To evaluate the results of elective isolated surgical aortic valve replacement (SAVR) on quality of life (QoL) in patients > 75 years. METHODS: 138 patients operated between January 2008 and December 2011 were included. The EuroQOL questionnaire (EQ-5D, EQ-VAS) was completed preoperatively, and 1- and 2-years postoperatively. The logistic EuroSCORE was used for risk stratification, the Corpus Christi Heart project criteria to assess physical activity. RESULTS: Mean age was 79.5 ± 2.8 years, mean risk 9.7 ± 5.4, hospital mortality 2.8 %. For 115 patients (83.3 %) the preoperative QoL information was complete. Fifty patients were classified as sedentary. In the first postoperative year 13 patients died, mostly sedentary patients (p = 0.046) with a low EQ-5D (p = 0.017). There was no QoL information on 32 survivors, mostly sedentary patients (p = 0.001). The 70 patients with QoL information showed an increased QoL (NS). Two years postoperatively, 16 patients died, significantly more sedentary patients (p = 0.015) with a low EQ-5D (p = 0.006). For 42 survivors, there was no QoL information; these were mostly sedentary patients (p = 0.021). The 57 patients with 2-year QoL information had an increased EQ-5D (NS) and EQ-VAS (p = 0.024). CONCLUSIONS: QoL increases after SAVR. However, the patients lost to follow-up were mostly sedentary or had a low preoperative QoL, which can lead to biased results.
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spelling pubmed-43521512015-03-11 Surgical aortic valve replacement in patients older than 75 years: is there really a quality of life benefit? van Laar, Charlotte Kievit, Peter C. Noyez, Luc Neth Heart J Original Article-e-learning BACKGROUND: To evaluate the results of elective isolated surgical aortic valve replacement (SAVR) on quality of life (QoL) in patients > 75 years. METHODS: 138 patients operated between January 2008 and December 2011 were included. The EuroQOL questionnaire (EQ-5D, EQ-VAS) was completed preoperatively, and 1- and 2-years postoperatively. The logistic EuroSCORE was used for risk stratification, the Corpus Christi Heart project criteria to assess physical activity. RESULTS: Mean age was 79.5 ± 2.8 years, mean risk 9.7 ± 5.4, hospital mortality 2.8 %. For 115 patients (83.3 %) the preoperative QoL information was complete. Fifty patients were classified as sedentary. In the first postoperative year 13 patients died, mostly sedentary patients (p = 0.046) with a low EQ-5D (p = 0.017). There was no QoL information on 32 survivors, mostly sedentary patients (p = 0.001). The 70 patients with QoL information showed an increased QoL (NS). Two years postoperatively, 16 patients died, significantly more sedentary patients (p = 0.015) with a low EQ-5D (p = 0.006). For 42 survivors, there was no QoL information; these were mostly sedentary patients (p = 0.021). The 57 patients with 2-year QoL information had an increased EQ-5D (NS) and EQ-VAS (p = 0.024). CONCLUSIONS: QoL increases after SAVR. However, the patients lost to follow-up were mostly sedentary or had a low preoperative QoL, which can lead to biased results. Bohn Stafleu van Loghum 2015-02-21 2015-03 /pmc/articles/PMC4352151/ /pubmed/25884084 http://dx.doi.org/10.1007/s12471-015-0660-2 Text en © The Author(s) 2015 https://creativecommons.org/licenses/by/4.0/ Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Article-e-learning
van Laar, Charlotte
Kievit, Peter C.
Noyez, Luc
Surgical aortic valve replacement in patients older than 75 years: is there really a quality of life benefit?
title Surgical aortic valve replacement in patients older than 75 years: is there really a quality of life benefit?
title_full Surgical aortic valve replacement in patients older than 75 years: is there really a quality of life benefit?
title_fullStr Surgical aortic valve replacement in patients older than 75 years: is there really a quality of life benefit?
title_full_unstemmed Surgical aortic valve replacement in patients older than 75 years: is there really a quality of life benefit?
title_short Surgical aortic valve replacement in patients older than 75 years: is there really a quality of life benefit?
title_sort surgical aortic valve replacement in patients older than 75 years: is there really a quality of life benefit?
topic Original Article-e-learning
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352151/
https://www.ncbi.nlm.nih.gov/pubmed/25884084
http://dx.doi.org/10.1007/s12471-015-0660-2
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