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Physicochemical and Biological Properties of Oxovanadium(IV), Cobalt(II) and Nickel(II) Complexes with Oxydiacetate Anions
The potentiometric and conductometric titration methods have been used to characterize the stability of series of VO(IV)-, Co(II)- and Ni(II)-oxydiacetato complexes in DMSO-water solutions containing 0–50 % (v/v) DMSO. The influence of DMSO as a co-solvent on the stability of the complexes as well a...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352194/ https://www.ncbi.nlm.nih.gov/pubmed/25488702 http://dx.doi.org/10.1007/s12011-014-0170-x |
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author | Wyrzykowski, Dariusz Kloska, Anna Pranczk, Joanna Szczepańska, Aneta Tesmar, Aleksandra Jacewicz, Dagmara Pilarski, Bogusław Chmurzyński, Lech |
author_facet | Wyrzykowski, Dariusz Kloska, Anna Pranczk, Joanna Szczepańska, Aneta Tesmar, Aleksandra Jacewicz, Dagmara Pilarski, Bogusław Chmurzyński, Lech |
author_sort | Wyrzykowski, Dariusz |
collection | PubMed |
description | The potentiometric and conductometric titration methods have been used to characterize the stability of series of VO(IV)-, Co(II)- and Ni(II)-oxydiacetato complexes in DMSO-water solutions containing 0–50 % (v/v) DMSO. The influence of DMSO as a co-solvent on the stability of the complexes as well as the oxydiacetic acid was evaluated. Furthermore, the reactivity of the complexes towards superoxide free radicals was assessed by employing the nitro blue tetrazolium (NBT) assay. The biological properties of the complexes were investigated in relation to their cytoprotective activity against the oxidative damage generated exogenously by using hydrogen peroxide in the Human Dermal Fibroblasts adult (HDFa) cell line as well as to their antimicrobial activity against the bacteria (Bacillus subtilis, Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis). The relationship between physicochemical and biological properties of the complexes was discussed. |
format | Online Article Text |
id | pubmed-4352194 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-43521942015-03-11 Physicochemical and Biological Properties of Oxovanadium(IV), Cobalt(II) and Nickel(II) Complexes with Oxydiacetate Anions Wyrzykowski, Dariusz Kloska, Anna Pranczk, Joanna Szczepańska, Aneta Tesmar, Aleksandra Jacewicz, Dagmara Pilarski, Bogusław Chmurzyński, Lech Biol Trace Elem Res Article The potentiometric and conductometric titration methods have been used to characterize the stability of series of VO(IV)-, Co(II)- and Ni(II)-oxydiacetato complexes in DMSO-water solutions containing 0–50 % (v/v) DMSO. The influence of DMSO as a co-solvent on the stability of the complexes as well as the oxydiacetic acid was evaluated. Furthermore, the reactivity of the complexes towards superoxide free radicals was assessed by employing the nitro blue tetrazolium (NBT) assay. The biological properties of the complexes were investigated in relation to their cytoprotective activity against the oxidative damage generated exogenously by using hydrogen peroxide in the Human Dermal Fibroblasts adult (HDFa) cell line as well as to their antimicrobial activity against the bacteria (Bacillus subtilis, Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis). The relationship between physicochemical and biological properties of the complexes was discussed. Springer US 2014-12-07 2015 /pmc/articles/PMC4352194/ /pubmed/25488702 http://dx.doi.org/10.1007/s12011-014-0170-x Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Article Wyrzykowski, Dariusz Kloska, Anna Pranczk, Joanna Szczepańska, Aneta Tesmar, Aleksandra Jacewicz, Dagmara Pilarski, Bogusław Chmurzyński, Lech Physicochemical and Biological Properties of Oxovanadium(IV), Cobalt(II) and Nickel(II) Complexes with Oxydiacetate Anions |
title | Physicochemical and Biological Properties of Oxovanadium(IV), Cobalt(II) and Nickel(II) Complexes with Oxydiacetate Anions |
title_full | Physicochemical and Biological Properties of Oxovanadium(IV), Cobalt(II) and Nickel(II) Complexes with Oxydiacetate Anions |
title_fullStr | Physicochemical and Biological Properties of Oxovanadium(IV), Cobalt(II) and Nickel(II) Complexes with Oxydiacetate Anions |
title_full_unstemmed | Physicochemical and Biological Properties of Oxovanadium(IV), Cobalt(II) and Nickel(II) Complexes with Oxydiacetate Anions |
title_short | Physicochemical and Biological Properties of Oxovanadium(IV), Cobalt(II) and Nickel(II) Complexes with Oxydiacetate Anions |
title_sort | physicochemical and biological properties of oxovanadium(iv), cobalt(ii) and nickel(ii) complexes with oxydiacetate anions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352194/ https://www.ncbi.nlm.nih.gov/pubmed/25488702 http://dx.doi.org/10.1007/s12011-014-0170-x |
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