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Results of Surgical Treatment of Schwannomas Arising from Extremities
Schwannomas are benign neoplasms derived from Schwann cells. In this work, we present our experience in operative management of schwannomas and analyse results of treatment. Clinical material consisted of 34 patients, in whom 44 schwannomas located in extremities were excised between 1985 and 2013....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352496/ https://www.ncbi.nlm.nih.gov/pubmed/25793198 http://dx.doi.org/10.1155/2015/547926 |
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author | Gosk, Jerzy Gutkowska, Olga Urban, Maciej Wnukiewicz, Witold Reichert, Paweł Ziółkowski, Piotr |
author_facet | Gosk, Jerzy Gutkowska, Olga Urban, Maciej Wnukiewicz, Witold Reichert, Paweł Ziółkowski, Piotr |
author_sort | Gosk, Jerzy |
collection | PubMed |
description | Schwannomas are benign neoplasms derived from Schwann cells. In this work, we present our experience in operative management of schwannomas and analyse results of treatment. Clinical material consisted of 34 patients, in whom 44 schwannomas located in extremities were excised between 1985 and 2013. Thirty-five tumours originated from major peripheral nerves and 9 from small nerve branches. Postoperatively, in the first group of tumours, pain resolved in 100%, paresthesias in 83.3%, and Hoffmann-Tinel sign in 91.6% of the patients. Improvement in motor function was noted in 28.5% of the cases, in sensory function: complete in 70%, and partial in 15%. The most frequently affected major peripheral nerves were the ulnar (11 tumours) and median (5 tumours) nerves. Schwannomas originating from small nerve branches were removed without identification of the site of origin. After their resection, definitive healing was achieved. Conclusions. (1) Schwannomas located in extremities arise predominantly from major peripheral nerves, most commonly the ulnar and median nerves. (2) Gradual tumour growth causes exacerbation of compression neuropathy, creating an indication for surgery. (3) In most cases, improvement in peripheral nerve function after excision of schwannoma is achieved. (4) The risk of new permanent postoperative neurological deficits is low. |
format | Online Article Text |
id | pubmed-4352496 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43524962015-03-19 Results of Surgical Treatment of Schwannomas Arising from Extremities Gosk, Jerzy Gutkowska, Olga Urban, Maciej Wnukiewicz, Witold Reichert, Paweł Ziółkowski, Piotr Biomed Res Int Clinical Study Schwannomas are benign neoplasms derived from Schwann cells. In this work, we present our experience in operative management of schwannomas and analyse results of treatment. Clinical material consisted of 34 patients, in whom 44 schwannomas located in extremities were excised between 1985 and 2013. Thirty-five tumours originated from major peripheral nerves and 9 from small nerve branches. Postoperatively, in the first group of tumours, pain resolved in 100%, paresthesias in 83.3%, and Hoffmann-Tinel sign in 91.6% of the patients. Improvement in motor function was noted in 28.5% of the cases, in sensory function: complete in 70%, and partial in 15%. The most frequently affected major peripheral nerves were the ulnar (11 tumours) and median (5 tumours) nerves. Schwannomas originating from small nerve branches were removed without identification of the site of origin. After their resection, definitive healing was achieved. Conclusions. (1) Schwannomas located in extremities arise predominantly from major peripheral nerves, most commonly the ulnar and median nerves. (2) Gradual tumour growth causes exacerbation of compression neuropathy, creating an indication for surgery. (3) In most cases, improvement in peripheral nerve function after excision of schwannoma is achieved. (4) The risk of new permanent postoperative neurological deficits is low. Hindawi Publishing Corporation 2015 2015-02-22 /pmc/articles/PMC4352496/ /pubmed/25793198 http://dx.doi.org/10.1155/2015/547926 Text en Copyright © 2015 Jerzy Gosk et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Gosk, Jerzy Gutkowska, Olga Urban, Maciej Wnukiewicz, Witold Reichert, Paweł Ziółkowski, Piotr Results of Surgical Treatment of Schwannomas Arising from Extremities |
title | Results of Surgical Treatment of Schwannomas Arising from Extremities |
title_full | Results of Surgical Treatment of Schwannomas Arising from Extremities |
title_fullStr | Results of Surgical Treatment of Schwannomas Arising from Extremities |
title_full_unstemmed | Results of Surgical Treatment of Schwannomas Arising from Extremities |
title_short | Results of Surgical Treatment of Schwannomas Arising from Extremities |
title_sort | results of surgical treatment of schwannomas arising from extremities |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352496/ https://www.ncbi.nlm.nih.gov/pubmed/25793198 http://dx.doi.org/10.1155/2015/547926 |
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