Cargando…

Results of Surgical Treatment of Schwannomas Arising from Extremities

Schwannomas are benign neoplasms derived from Schwann cells. In this work, we present our experience in operative management of schwannomas and analyse results of treatment. Clinical material consisted of 34 patients, in whom 44 schwannomas located in extremities were excised between 1985 and 2013....

Descripción completa

Detalles Bibliográficos
Autores principales: Gosk, Jerzy, Gutkowska, Olga, Urban, Maciej, Wnukiewicz, Witold, Reichert, Paweł, Ziółkowski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352496/
https://www.ncbi.nlm.nih.gov/pubmed/25793198
http://dx.doi.org/10.1155/2015/547926
_version_ 1782360466637455360
author Gosk, Jerzy
Gutkowska, Olga
Urban, Maciej
Wnukiewicz, Witold
Reichert, Paweł
Ziółkowski, Piotr
author_facet Gosk, Jerzy
Gutkowska, Olga
Urban, Maciej
Wnukiewicz, Witold
Reichert, Paweł
Ziółkowski, Piotr
author_sort Gosk, Jerzy
collection PubMed
description Schwannomas are benign neoplasms derived from Schwann cells. In this work, we present our experience in operative management of schwannomas and analyse results of treatment. Clinical material consisted of 34 patients, in whom 44 schwannomas located in extremities were excised between 1985 and 2013. Thirty-five tumours originated from major peripheral nerves and 9 from small nerve branches. Postoperatively, in the first group of tumours, pain resolved in 100%, paresthesias in 83.3%, and Hoffmann-Tinel sign in 91.6% of the patients. Improvement in motor function was noted in 28.5% of the cases, in sensory function: complete in 70%, and partial in 15%. The most frequently affected major peripheral nerves were the ulnar (11 tumours) and median (5 tumours) nerves. Schwannomas originating from small nerve branches were removed without identification of the site of origin. After their resection, definitive healing was achieved. Conclusions. (1) Schwannomas located in extremities arise predominantly from major peripheral nerves, most commonly the ulnar and median nerves. (2) Gradual tumour growth causes exacerbation of compression neuropathy, creating an indication for surgery. (3) In most cases, improvement in peripheral nerve function after excision of schwannoma is achieved. (4) The risk of new permanent postoperative neurological deficits is low.
format Online
Article
Text
id pubmed-4352496
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-43524962015-03-19 Results of Surgical Treatment of Schwannomas Arising from Extremities Gosk, Jerzy Gutkowska, Olga Urban, Maciej Wnukiewicz, Witold Reichert, Paweł Ziółkowski, Piotr Biomed Res Int Clinical Study Schwannomas are benign neoplasms derived from Schwann cells. In this work, we present our experience in operative management of schwannomas and analyse results of treatment. Clinical material consisted of 34 patients, in whom 44 schwannomas located in extremities were excised between 1985 and 2013. Thirty-five tumours originated from major peripheral nerves and 9 from small nerve branches. Postoperatively, in the first group of tumours, pain resolved in 100%, paresthesias in 83.3%, and Hoffmann-Tinel sign in 91.6% of the patients. Improvement in motor function was noted in 28.5% of the cases, in sensory function: complete in 70%, and partial in 15%. The most frequently affected major peripheral nerves were the ulnar (11 tumours) and median (5 tumours) nerves. Schwannomas originating from small nerve branches were removed without identification of the site of origin. After their resection, definitive healing was achieved. Conclusions. (1) Schwannomas located in extremities arise predominantly from major peripheral nerves, most commonly the ulnar and median nerves. (2) Gradual tumour growth causes exacerbation of compression neuropathy, creating an indication for surgery. (3) In most cases, improvement in peripheral nerve function after excision of schwannoma is achieved. (4) The risk of new permanent postoperative neurological deficits is low. Hindawi Publishing Corporation 2015 2015-02-22 /pmc/articles/PMC4352496/ /pubmed/25793198 http://dx.doi.org/10.1155/2015/547926 Text en Copyright © 2015 Jerzy Gosk et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Gosk, Jerzy
Gutkowska, Olga
Urban, Maciej
Wnukiewicz, Witold
Reichert, Paweł
Ziółkowski, Piotr
Results of Surgical Treatment of Schwannomas Arising from Extremities
title Results of Surgical Treatment of Schwannomas Arising from Extremities
title_full Results of Surgical Treatment of Schwannomas Arising from Extremities
title_fullStr Results of Surgical Treatment of Schwannomas Arising from Extremities
title_full_unstemmed Results of Surgical Treatment of Schwannomas Arising from Extremities
title_short Results of Surgical Treatment of Schwannomas Arising from Extremities
title_sort results of surgical treatment of schwannomas arising from extremities
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352496/
https://www.ncbi.nlm.nih.gov/pubmed/25793198
http://dx.doi.org/10.1155/2015/547926
work_keys_str_mv AT goskjerzy resultsofsurgicaltreatmentofschwannomasarisingfromextremities
AT gutkowskaolga resultsofsurgicaltreatmentofschwannomasarisingfromextremities
AT urbanmaciej resultsofsurgicaltreatmentofschwannomasarisingfromextremities
AT wnukiewiczwitold resultsofsurgicaltreatmentofschwannomasarisingfromextremities
AT reichertpaweł resultsofsurgicaltreatmentofschwannomasarisingfromextremities
AT ziołkowskipiotr resultsofsurgicaltreatmentofschwannomasarisingfromextremities