Insulin Increases Sestrin 2 Content by Reducing Its Degradation through the PI(3)K/mTOR Signaling Pathway

Sestrin (SESN) is known as a cysteine sulfinic acid reductase. Recently, nonredox functions of SESN in metabolic regulation and antitumor property have been recognized. While mechanisms underlying the expression of SESN are not fully understood. Here we report that insulin markedly increased SESN2 l...

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Detalles Bibliográficos
Autores principales: Chai, Dandan, Wang, Guoyu, Zhou, Ziyu, Yang, Hanyan, Yu, Zhiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352509/
https://www.ncbi.nlm.nih.gov/pubmed/25792980
http://dx.doi.org/10.1155/2015/505849

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