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Autocrine prostaglandin E(2) signaling promotes promonocytic leukemia cell survival via COX-2 expression and MAPK pathway

The COX-2/PGE(2) pathway has been implicated in the occurrence and progression of cancer. The underlying mechanisms facilitating the production of COX-2 and its mediator, PGE(2), in cancer survival remain unknown. Herein, we investigated PGE(2)-induced COX-2 expression and signaling in HL-60 cells f...

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Detalles Bibliográficos
Autores principales:	Shehzad, Adeeb, Lee, Jaetae, Lee, Young Sup
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2015
Materias:	Research-Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352612/ https://www.ncbi.nlm.nih.gov/pubmed/24965577 http://dx.doi.org/10.5483/BMBRep.2015.48.2.081

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