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Irisin – a myth rather than an exercise-inducible myokine
The myokine irisin is supposed to be cleaved from a transmembrane precursor, FNDC5 (fibronectin type III domain containing 5), and to mediate beneficial effects of exercise on human metabolism. However, evidence for irisin circulating in blood is largely based on commercial ELISA kits which are base...
Autores principales: | Albrecht, Elke, Norheim, Frode, Thiede, Bernd, Holen, Torgeir, Ohashi, Tomoo, Schering, Lisa, Lee, Sindre, Brenmoehl, Julia, Thomas, Selina, Drevon, Christian A., Erickson, Harold P., Maak, Steffen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352853/ https://www.ncbi.nlm.nih.gov/pubmed/25749243 http://dx.doi.org/10.1038/srep08889 |
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