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Bacterial genome reduction using the progressive clustering of deletions via yeast sexual cycling

The availability of genetically tractable organisms with simple genomes is critical for the rapid, systems-level understanding of basic biological processes. Mycoplasma bacteria, with the smallest known genomes among free-living cellular organisms, are ideal models for this purpose, but the natural...

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Detalles Bibliográficos
Autores principales: Suzuki, Yo, Assad-Garcia, Nacyra, Kostylev, Maxim, Noskov, Vladimir N., Wise, Kim S., Karas, Bogumil J., Stam, Jason, Montague, Michael G., Hanly, Timothy J., Enriquez, Nico J., Ramon, Adi, Goldgof, Gregory M., Richter, R. Alexander, Vashee, Sanjay, Chuang, Ray-Yuan, Winzeler, Elizabeth A., Hutchison, Clyde A., Gibson, Daniel G., Smith, Hamilton O., Glass, John I., Venter, J. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352883/
https://www.ncbi.nlm.nih.gov/pubmed/25654978
http://dx.doi.org/10.1101/gr.182477.114