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Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn's Disease

Here we present an eleven-year-old male patient who had been diagnosed with common variable immunodeficiency (CVID) three years ago due to recurrent sinopulmonary infections. Two years later he had been diagnosed with Crohn's disease (CD) due to diarrhea episodes which were unresponsive to the...

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Autores principales: Ünal, Betül, Başsorgun, Cumhur İbrahim, Çil Gönülcü, Sinem, Uçar, Aslı, Çelik, Fatih, Elpek, Gülsüm Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352901/
https://www.ncbi.nlm.nih.gov/pubmed/25802525
http://dx.doi.org/10.1155/2015/348204
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author Ünal, Betül
Başsorgun, Cumhur İbrahim
Çil Gönülcü, Sinem
Uçar, Aslı
Çelik, Fatih
Elpek, Gülsüm Özlem
author_facet Ünal, Betül
Başsorgun, Cumhur İbrahim
Çil Gönülcü, Sinem
Uçar, Aslı
Çelik, Fatih
Elpek, Gülsüm Özlem
author_sort Ünal, Betül
collection PubMed
description Here we present an eleven-year-old male patient who had been diagnosed with common variable immunodeficiency (CVID) three years ago due to recurrent sinopulmonary infections. Two years later he had been diagnosed with Crohn's disease (CD) due to diarrhea episodes which were unresponsive to the treatment. Depending on the active gastrointestinal bleeding and perforation he underwent total colectomy. Despite immunoglobulin and antiviral therapies, general condition of patient deteriorated and he died in the postoperative seventh day. Laboratory analysis was seronegative. CMV inclusion containing cells were detected in postmortem biopsies taken from liver, lungs, and lymph nodes.
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spelling pubmed-43529012015-03-23 Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn's Disease Ünal, Betül Başsorgun, Cumhur İbrahim Çil Gönülcü, Sinem Uçar, Aslı Çelik, Fatih Elpek, Gülsüm Özlem Case Rep Med Case Report Here we present an eleven-year-old male patient who had been diagnosed with common variable immunodeficiency (CVID) three years ago due to recurrent sinopulmonary infections. Two years later he had been diagnosed with Crohn's disease (CD) due to diarrhea episodes which were unresponsive to the treatment. Depending on the active gastrointestinal bleeding and perforation he underwent total colectomy. Despite immunoglobulin and antiviral therapies, general condition of patient deteriorated and he died in the postoperative seventh day. Laboratory analysis was seronegative. CMV inclusion containing cells were detected in postmortem biopsies taken from liver, lungs, and lymph nodes. Hindawi Publishing Corporation 2015 2015-02-23 /pmc/articles/PMC4352901/ /pubmed/25802525 http://dx.doi.org/10.1155/2015/348204 Text en Copyright © 2015 Betül Ünal et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ünal, Betül
Başsorgun, Cumhur İbrahim
Çil Gönülcü, Sinem
Uçar, Aslı
Çelik, Fatih
Elpek, Gülsüm Özlem
Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn's Disease
title Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn's Disease
title_full Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn's Disease
title_fullStr Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn's Disease
title_full_unstemmed Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn's Disease
title_short Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn's Disease
title_sort cytomegalovirus colitis with common variable immunodeficiency and crohn's disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352901/
https://www.ncbi.nlm.nih.gov/pubmed/25802525
http://dx.doi.org/10.1155/2015/348204
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