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Gene activation-associated long noncoding RNAs function in mouse preimplantation development

In mice, zygotic activation occurs for a wide variety of genes, mainly at the 2-cell stage. Long noncoding RNAs (lncRNAs) are increasingly being recognized as modulators of gene expression. In this study, directional RNA-seq of MII oocytes and 2-cell embryos identified more than 1000 divergently tra...

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Detalles Bibliográficos
Autores principales: Hamazaki, Nobuhiko, Uesaka, Masahiro, Nakashima, Kinichi, Agata, Kiyokazu, Imamura, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352986/
https://www.ncbi.nlm.nih.gov/pubmed/25633350
http://dx.doi.org/10.1242/dev.116996