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Comparison between intravenous paracetamol and fentanyl for intraoperative and postoperative pain relief in dilatation and evacuation: Prospective, randomized interventional trial

BACKGROUND AND AIMS: Dilatation and Evacuation procedure involves pain, for which pain control measures need to be undertaken. The purpose of this study was to compare paracetamol with fentanyl for pain relief in dilatation and curettage procedures. MATERIALS AND METHODS: Sixty female patients were...

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Autores principales: Ali, Muhammad Asghar, Shamim, Faisal, Chughtai, Shakaib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353154/
https://www.ncbi.nlm.nih.gov/pubmed/25788774
http://dx.doi.org/10.4103/0970-9185.150542
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author Ali, Muhammad Asghar
Shamim, Faisal
Chughtai, Shakaib
author_facet Ali, Muhammad Asghar
Shamim, Faisal
Chughtai, Shakaib
author_sort Ali, Muhammad Asghar
collection PubMed
description BACKGROUND AND AIMS: Dilatation and Evacuation procedure involves pain, for which pain control measures need to be undertaken. The purpose of this study was to compare paracetamol with fentanyl for pain relief in dilatation and curettage procedures. MATERIALS AND METHODS: Sixty female patients were randomly included during the period from March 1, 2012 to February 28, 2013. All patients had received oral midazolam 7.5 mg as a premedication 30 min before procedure in the ward. Group P had received intravenous (IV) paracetamol 15 mg/kg in the waiting area of the operating room 15 min before starting the procedure. Group F had received IV fentanyl 2 ug/kg/min at induction of anesthesia. Pain scores on a numerical rating scale at 5, 15, and 30 min intervals after surgery were recorded. RESULTS: Mild pain was commonly observed in both groups, an insignificant difference between groups. CONCLUSION: The study demonstrates the usefulness of IV paracetamol which may be as effective as fentanyl in dilation and curettage procedures.
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spelling pubmed-43531542015-03-18 Comparison between intravenous paracetamol and fentanyl for intraoperative and postoperative pain relief in dilatation and evacuation: Prospective, randomized interventional trial Ali, Muhammad Asghar Shamim, Faisal Chughtai, Shakaib J Anaesthesiol Clin Pharmacol Original Article BACKGROUND AND AIMS: Dilatation and Evacuation procedure involves pain, for which pain control measures need to be undertaken. The purpose of this study was to compare paracetamol with fentanyl for pain relief in dilatation and curettage procedures. MATERIALS AND METHODS: Sixty female patients were randomly included during the period from March 1, 2012 to February 28, 2013. All patients had received oral midazolam 7.5 mg as a premedication 30 min before procedure in the ward. Group P had received intravenous (IV) paracetamol 15 mg/kg in the waiting area of the operating room 15 min before starting the procedure. Group F had received IV fentanyl 2 ug/kg/min at induction of anesthesia. Pain scores on a numerical rating scale at 5, 15, and 30 min intervals after surgery were recorded. RESULTS: Mild pain was commonly observed in both groups, an insignificant difference between groups. CONCLUSION: The study demonstrates the usefulness of IV paracetamol which may be as effective as fentanyl in dilation and curettage procedures. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4353154/ /pubmed/25788774 http://dx.doi.org/10.4103/0970-9185.150542 Text en Copyright: © Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ali, Muhammad Asghar
Shamim, Faisal
Chughtai, Shakaib
Comparison between intravenous paracetamol and fentanyl for intraoperative and postoperative pain relief in dilatation and evacuation: Prospective, randomized interventional trial
title Comparison between intravenous paracetamol and fentanyl for intraoperative and postoperative pain relief in dilatation and evacuation: Prospective, randomized interventional trial
title_full Comparison between intravenous paracetamol and fentanyl for intraoperative and postoperative pain relief in dilatation and evacuation: Prospective, randomized interventional trial
title_fullStr Comparison between intravenous paracetamol and fentanyl for intraoperative and postoperative pain relief in dilatation and evacuation: Prospective, randomized interventional trial
title_full_unstemmed Comparison between intravenous paracetamol and fentanyl for intraoperative and postoperative pain relief in dilatation and evacuation: Prospective, randomized interventional trial
title_short Comparison between intravenous paracetamol and fentanyl for intraoperative and postoperative pain relief in dilatation and evacuation: Prospective, randomized interventional trial
title_sort comparison between intravenous paracetamol and fentanyl for intraoperative and postoperative pain relief in dilatation and evacuation: prospective, randomized interventional trial
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353154/
https://www.ncbi.nlm.nih.gov/pubmed/25788774
http://dx.doi.org/10.4103/0970-9185.150542
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