Cargando…

Accumulation of Advanced Glycation End-Products and Activation of the SCAP/SREBP Lipogenetic Pathway Occur in Diet-Induced Obese Mouse Skeletal Muscle

Aim of this study was to investigate whether advanced glycation end-products (AGEs) accumulate in skeletal myofibers of two different animal models of diabesity and whether this accumulation could be associated to myosteatosis. Male C57Bl/6j mice and leptin-deficient ob/ob mice were divided into thr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mastrocola, Raffaella, Collino, Massimo, Nigro, Debora, Chiazza, Fausto, D’Antona, Giuseppe, Aragno, Manuela, Minetto, Marco A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353621/ https://www.ncbi.nlm.nih.gov/pubmed/25750996 http://dx.doi.org/10.1371/journal.pone.0119587

Ejemplares similares

Variability in Myosteatosis and Insulin Resistance Induced by High-Fat Diet in Mouse Skeletal Muscles
por: Collino, Massimo, et al.
Publicado: (2014)

Effects of vitamin D on insulin resistance and myosteatosis in diet-induced obese mice
por: Benetti, Elisa, et al.
Publicado: (2018)

High Sugar Intake and Development of Skeletal Muscle Insulin Resistance and Inflammation in Mice: A Protective Role for PPAR-δ Agonism
por: Benetti, Elisa, et al.
Publicado: (2013)

Maladaptive Modulations of NLRP3 Inflammasome and Cardioprotective Pathways Are Involved in Diet-Induced Exacerbation of Myocardial Ischemia/Reperfusion Injury in Mice
por: Mastrocola, Raffaella, et al.
Publicado: (2016)

Dietary Sugars and Endogenous Formation of Advanced Glycation Endproducts: Emerging Mechanisms of Disease
por: Aragno, Manuela, et al.
Publicado: (2017)

Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways
por: Mastrocola, Raffaella, et al.
Publicado: (2016)

Reduced Susceptibility to Sugar-Induced Metabolic Derangements and Impairments of Myocardial Redox Signaling in Mice Chronically Fed with D-Tagatose when Compared to Fructose
por: Collotta, Debora, et al.
Publicado: (2018)

Effects of Exogenous Dietary Advanced Glycation End Products on the Cross-Talk Mechanisms Linking Microbiota to Metabolic Inflammation
por: Mastrocola, Raffaella, et al.
Publicado: (2020)

The SCAP/SREBP Pathway: A Mediator of Hepatic Steatosis
por: Moon, Young-Ah
Publicado: (2017)

Deletion of RAGE fails to prevent hepatosteatosis in obese mice due to impairment of other AGEs receptors and detoxifying systems
por: Wouters, Kristiaan, et al.
Publicado: (2021)

Baricitinib counteracts metaflammation, thus protecting against diet-induced metabolic abnormalities in mice
por: Collotta, Debora, et al.
Publicado: (2020)

Cholesterol Contributes to Diabetic Nephropathy through SCAP-SREBP-2 Pathway
por: Sun, Hong, et al.
Publicado: (2013)

GP73 regulates Hepatic Steatosis by enhancing SCAP-SREBPs interaction
por: Yang, Xiaoli, et al.
Publicado: (2017)

Protective Effects of Pyridoxamine Supplementation in the Early Stages of Diet-Induced Kidney Dysfunction
por: Chiazza, F., et al.
Publicado: (2017)

Inhibiting SCAP/SREBP exacerbates liver injury and carcinogenesis in murine nonalcoholic steatohepatitis
por: Kawamura, Satoshi, et al.
Publicado: (2022)

The Gene-Gene Interaction of INSIG-SCAP-SREBP Pathway on the Risk of Obesity in Chinese Children
por: Liu, Fang-Hong, et al.
Publicado: (2014)

PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus
por: Xu, Daqian, et al.
Publicado: (2015)

Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization
por: Gong, Xin, et al.
Publicado: (2016)

Lipogenetic and glycolytic enzyme activities in carcinoma and nonmalignant diseases of the human breast.
por: Szutowicz, A., et al.
Publicado: (1979)

The Chromatin Remodeling Protein BRG1 Regulates SREBP Maturation by Activating SCAP Transcription in Hepatocytes
por: Kong, Ming, et al.
Publicado: (2021)

Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumor growth
por: Cheng, Chunming, et al.
Publicado: (2022)

Epithelial SCAP/INSIG/SREBP Signaling Regulates Multiple Biological Processes during Perinatal Lung Maturation
por: Bridges, James P., et al.
Publicado: (2014)

Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition
por: Gong, Xin, et al.
Publicado: (2015)

Cideb controls sterol‐regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites
por: Su, Lu, et al.
Publicado: (2019)

RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression
por: Guo, Di, et al.
Publicado: (2019)

Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes
por: Purvis, Gareth S. D., et al.
Publicado: (2019)

Quercetin improves lipid metabolism via SCAP-SREBP2-LDLr signaling pathway in early stage diabetic nephropathy
por: Jiang, Xiyuan, et al.
Publicado: (2019)

Long-Term Disturbed Expression and DNA Methylation of SCAP/SREBP Signaling in the Mouse Lung From Assisted Reproductive Technologies
por: Le, Fang, et al.
Publicado: (2021)

Alpha-2A Adrenoceptor Agonist Guanfacine Restores Diuretic Efficiency in Experimental Cirrhotic Ascites: Comparison with Clonidine
por: Sansoè, Giovanni, et al.
Publicado: (2016)

Liraglutide reduces lipogenetic signals in visceral adipose of db/db mice with AMPK activation and Akt suppression
por: Shao, Yimin, et al.
Publicado: (2015)

Pharmacological Inhibition of FAK-Pyk2 Pathway Protects Against Organ Damage and Prolongs the Survival of Septic Mice
por: Alves, Gustavo Ferreira, et al.
Publicado: (2022)

Role of Chymase in the Development of Liver Cirrhosis and Its Complications: Experimental and Human Data
por: Sansoè, Giovanni, et al.
Publicado: (2016)

Anti-Inflammatory Effects of Ang-(1-7) in Ameliorating HFD-Induced Renal Injury through LDLr-SREBP2-SCAP Pathway
por: Zheng, Yaning, et al.
Publicado: (2015)

Effect of Tetramethylpyrazine on Atherosclerosis and SCAP/SREBP-1c Signaling Pathway in ApoE(−/−) Mice Fed with a High-Fat Diet
por: Zhang, Ying, et al.
Publicado: (2017)

LncGSAR Controls Ovarian Granulosa Cell Steroidogenesis via Sponging MiR-125b to Activate SCAP/SREBP Pathway
por: Wang, Yong, et al.
Publicado: (2022)

Ticagrelor Conditioning Effects Are Not Additive to Cardioprotection Induced by Direct NLRP3 Inflammasome Inhibition: Role of RISK, NLRP3, and Redox Cascades
por: Penna, Claudia, et al.
Publicado: (2020)

The NLRP3 Inflammasome as a Novel Player of the Intercellular Crosstalk in Metabolic Disorders
por: Benetti, Elisa, et al.
Publicado: (2013)

Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanisms
por: Aragno, Manuela, et al.
Publicado: (2012)

SREBP activation contributes to fatty acid accumulations in necroptosis
por: Lu, Daniel, et al.
Publicado: (2023)

The cellular function of SCAP in metabolic signaling
por: Lee, Sun Hee, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7bvld4afsgk14rjt8kave9iun6