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Litsea japonica Extract Inhibits Aldose Reductase Activity and Hyperglycemia-Induced Lenticular Sorbitol Accumulation in db/db Mice
Aldose reductase (AR) is the first and rate-limiting enzyme of the polyol pathway. AR-dependent synthesis of excess polyols leads to lens opacification in diabetic cataract. The purpose of this study is to investigate the protective effect of Litsea japonica extract (LJE) on diabetes-induced lens op...
Autores principales: | Kim, Junghyun, Kim, Chan-Sik, Sohn, Eunjin, Lee, Yun Mi, Jo, Kyuhyung, Kim, Jin Sook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353661/ https://www.ncbi.nlm.nih.gov/pubmed/25802544 http://dx.doi.org/10.1155/2015/747830 |
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