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Litsea japonica Extract Inhibits Aldose Reductase Activity and Hyperglycemia-Induced Lenticular Sorbitol Accumulation in db/db Mice

Aldose reductase (AR) is the first and rate-limiting enzyme of the polyol pathway. AR-dependent synthesis of excess polyols leads to lens opacification in diabetic cataract. The purpose of this study is to investigate the protective effect of Litsea japonica extract (LJE) on diabetes-induced lens op...

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Detalles Bibliográficos
Autores principales: Kim, Junghyun, Kim, Chan-Sik, Sohn, Eunjin, Lee, Yun Mi, Jo, Kyuhyung, Kim, Jin Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353661/
https://www.ncbi.nlm.nih.gov/pubmed/25802544
http://dx.doi.org/10.1155/2015/747830

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