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Deficiency in Th2 Cytokine Responses Exacerbate Orthopoxvirus Infection
Ectromelia virus (ECTV) causes mousepox in mice, a disease very similar to smallpox in humans. ECTV and variola virus (VARV), the agent of smallpox, are closely related orthopoxviruses. Mousepox is an excellent small animal model to study the genetic and immunologic basis for resistance and suscepti...
Autores principales: | Sakala, Isaac G., Chaudhri, Geeta, Eldi, Preethi, Buller, R. Mark, Karupiah, Gunasegaran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353717/ https://www.ncbi.nlm.nih.gov/pubmed/25751266 http://dx.doi.org/10.1371/journal.pone.0118685 |
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