Cargando…

Piperlongumine reverses doxorubicin resistance through the PI3K/Akt signaling pathway in K562/A02 human leukemia cells

Drug resistance is an important obstacle to human leukemia therapeutics. Piperlongumine has previously demonstrated the ability to suppress certain human tumor processes; however, the ability of piperlongumine to reverse the drug resistance of human leukemia and its mechanism of action have not yet...

Descripción completa

Detalles Bibliográficos
Autores principales:	KANG, QINGWEI, YAN, SHU
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353808/ https://www.ncbi.nlm.nih.gov/pubmed/25780433 http://dx.doi.org/10.3892/etm.2015.2254

Ejemplares similares

Silencing of the CrkL gene reverses the doxorubicin resistance of K562/ADR cells through regulating PI3K/Akt/MRP1 signaling
por: Yu, Jiang, et al.
Publicado: (2021)

Role of the aclacinomycin A--doxorubicin association in reversal of doxorubicin resistance in K562 tumour cells.
por: Millot, J. M., et al.
Publicado: (1989)

In Vitro Antileukemia Activity of ZSTK474 on K562 and Multidrug Resistant K562/A02 Cells
por: Zhou, Qianxiang, et al.
Publicado: (2016)

Piperlongumine induces apoptosis and autophagy in leukemic cells through targeting the PI3K/Akt/mTOR and p38 signaling pathways
por: Wang, Hongfei, et al.
Publicado: (2018)

Thymoquinone Inhibits JAK/STAT and PI3K/Akt/ mTOR Signaling Pathways in MV4-11 and K562 Myeloid Leukemia Cells
por: Al-Rawashde, Futoon Abedrabbu, et al.
Publicado: (2022)

8-Hydroxydaidzein Downregulates JAK/STAT, MMP, Oxidative Phosphorylation, and PI3K/AKT Pathways in K562 Cells
por: Wu, Pei-Shan, et al.
Publicado: (2021)

The Mechanism of Bufalin-Induced Apoptosis of K562/A02
por: Xie, Ying, et al.
Publicado: (2019)

Rapamycin enhanced the antitumor effects of doxorubicin in myelogenous leukemia K562 cells by downregulating the mTOR/p70S6K pathway
por: Li, Jie, et al.
Publicado: (2019)

Dual PI3K/mTOR inhibitor NVP-BEZ235 decreases the proliferation of doxorubicin-resistant K562 cells
por: Li, Jie, et al.
Publicado: (2021)

Tuberostemonine reverses multidrug resistance in chronic myelogenous leukemia cells K562/ADR
por: Wang, Yu Jia, et al.
Publicado: (2017)

Ketoconazole Reverses Imatinib Resistance in Human Chronic Myelogenous Leukemia K562 Cells
por: Prado-Carrillo, Omar, et al.
Publicado: (2022)

Emodin Exerts an Antiapoptotic Effect on Human Chronic Myelocytic Leukemia K562 Cell Lines by Targeting the PTEN/PI3K-AKT Signaling Pathway and Deleting BCR-ABL
por: Wang, Chun-Guang, et al.
Publicado: (2016)

Reversal of multidrug resistance by 5,5’-dimethoxylariciresinol-4-O-β-D-glucoside in doxorubicin-resistant human leukemia K562/DOX
por: Wang, Tian-Xiao, et al.
Publicado: (2013)

Pyrimidine-5-carbonitrile based potential anticancer agents as apoptosis inducers through PI3K/AKT axis inhibition in leukaemia K562
por: El-Dydamony, Nehad M., et al.
Publicado: (2022)

Genomic amplification of chromosome 7 in the Doxorubicin resistant K562 cell line
por: Ibrahim, Sara.M, et al.
Publicado: (2018)

Benazepril hydrochloride protects against doxorubicin cardiotoxicity by regulating the PI3K/Akt pathway
por: Zhan, Lan, et al.
Publicado: (2021)

Dexrazoxane significantly impairs the induction of doxorubicin resistance in the human leukaemia line, K562
por: Sargent, J M, et al.
Publicado: (2001)

Apoptotic Mechanism of Human Leukemia K562/A02 Cells Induced by Magnetic Ferroferric Oxide Nanoparticles Loaded with Wogonin
por: Peng, Miao-Xin, et al.
Publicado: (2016)

Determination of the relationship between doxorubicin resistance and Wnt signaling pathway in HeLa and K562 cell lines
por: Mutlu, Pelin, et al.
Publicado: (2018)

Effect of magnetic nanoparticles of Fe(3)O(4) and wogonin on the reversal of multidrug resistance in K562/A02 cell line
por: Cheng, Jian, et al.
Publicado: (2012)

Astragalus Polysaccharide Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the PI3k/Akt and p38MAPK Pathways
por: Cao, Yuan, et al.
Publicado: (2014)

Induction of Erythroid Differentiation by 5‐Fluorouracil in K562 Leukemia Cells
por: Yang, Ya‐Wun, et al.
Publicado: (1995)

Targeted regulation of MiR-98 on E2F1 increases chemosensitivity of leukemia cells K562/A02
por: Huang, Yingdan, et al.
Publicado: (2017)

Hypericin-mediated photodynamic therapy induces apoptosis in K562 human leukemia cells through JNK pathway modulation
por: XU, YIXIAO, et al.
Publicado: (2015)

Knockdown of NUDT21 inhibits proliferation and promotes apoptosis of human K562 leukemia cells through ERK pathway
por: Zhang, Lan, et al.
Publicado: (2018)

Verteporfin reverses progestin resistance through YAP/TAZ-PI3K-Akt pathway in endometrial carcinoma
por: Wei, Lina, et al.
Publicado: (2023)

Inhibition of p38 MAPK diminishes doxorubicin-induced drug resistance associated with P-glycoprotein in human leukemia K562 cells
por: Chen, Yinghui, et al.
Publicado: (2012)

Reversal in multidrug resistance by magnetic nanoparticle of Fe(3)O(4) loaded with adriamycin and tetrandrine in K562/A02 leukemic cells
por: Chen, Baoan, et al.
Publicado: (2008)

Effect of magnetic nanoparticles of Fe(3)O(4) and 5-bromotetrandrine on reversal of multidrug resistance in K562/A02 leukemic cells
por: Cheng, Jian, et al.
Publicado: (2009)

靶向抑制miRNA-21对K562细胞增殖及PTEN-PI3K/AKT通路的影响
Publicado: (2016)

PTEN Regulates BCRP/ABCG2 and the Side Population through the PI3K/Akt Pathway in Chronic Myeloid Leukemia
por: Huang, Fang-Fang, et al.
Publicado: (2014)

Thymoquinone Induces Downregulation of BCR-ABL/JAK/STAT Pathway and Apoptosis in K562 Leukemia Cells
por: Al-Rawashde, Futoon Abedrabbu, et al.
Publicado: (2021)

Antiproliferative Effect of Aaptamine on Human Chronic Myeloid Leukemia K562 Cells
por: Jin, Meihua, et al.
Publicado: (2011)

Anticancer activity of Pupalia lappacea on chronic myeloid leukemia K562 cells
por: Ravi, Alvala, et al.
Publicado: (2012)

Tendency of K562 Chronic Myeloid Leukemia Cells Towards Cell Reprogramming
por: Yılmazer Aktuna, Açelya
Publicado: (2018)

The Effect of Polyhydroxy Fullerene Derivative on Human Myeloid Leukemia K562 Cells
por: Guo, Wei, et al.
Publicado: (2022)

Ursolic acid-mediated apoptosis of K562 cells involves Stat5/Akt pathway inhibition through the induction of Gfi-1
por: Lin, Ze, et al.
Publicado: (2016)

Ampelopsin Inhibits Cell Proliferation and Induces Apoptosis in HL60 and K562 Leukemia Cells by Downregulating AKT and NF-κB Signaling Pathways
por: Han, Jang Mi, et al.
Publicado: (2021)

Effect of Eriodictyol on Retinoblastoma via the PI3K/Akt Pathway
por: Wen, Shu, et al.
Publicado: (2021)

Apoptin‐derived peptide reverses cisplatin resistance in gastric cancer through the PI3K–AKT signaling pathway
por: Zhou, Danyang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_399frdfmh8vlnj8fblo3tj5gvh