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Bioinformatics Tools for Small Genomes, Such as Hepatitis B Virus

DNA sequence analysis is undertaken in many biological research laboratories. The workflow consists of several steps involving the bioinformatic processing of biological data. We have developed a suite of web-based online bioinformatic tools to assist with processing, analysis and curation of DNA se...

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Detalles Bibliográficos
Autores principales: Bell, Trevor G., Kramvis, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353916/
https://www.ncbi.nlm.nih.gov/pubmed/25690798
http://dx.doi.org/10.3390/v7020781
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author Bell, Trevor G.
Kramvis, Anna
author_facet Bell, Trevor G.
Kramvis, Anna
author_sort Bell, Trevor G.
collection PubMed
description DNA sequence analysis is undertaken in many biological research laboratories. The workflow consists of several steps involving the bioinformatic processing of biological data. We have developed a suite of web-based online bioinformatic tools to assist with processing, analysis and curation of DNA sequence data. Most of these tools are genome-agnostic, with two tools specifically designed for hepatitis B virus sequence data. Tools in the suite are able to process sequence data from Sanger sequencing, ultra-deep amplicon resequencing (pyrosequencing) and chromatograph (trace files), as appropriate. The tools are available online at no cost and are aimed at researchers without specialist technical computer knowledge. The tools can be accessed at http://hvdr.bioinf.wits.ac.za/SmallGenomeTools, and the source code is available online at https://github.com/DrTrevorBell/SmallGenomeTools.
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spelling pubmed-43539162015-04-10 Bioinformatics Tools for Small Genomes, Such as Hepatitis B Virus Bell, Trevor G. Kramvis, Anna Viruses Article DNA sequence analysis is undertaken in many biological research laboratories. The workflow consists of several steps involving the bioinformatic processing of biological data. We have developed a suite of web-based online bioinformatic tools to assist with processing, analysis and curation of DNA sequence data. Most of these tools are genome-agnostic, with two tools specifically designed for hepatitis B virus sequence data. Tools in the suite are able to process sequence data from Sanger sequencing, ultra-deep amplicon resequencing (pyrosequencing) and chromatograph (trace files), as appropriate. The tools are available online at no cost and are aimed at researchers without specialist technical computer knowledge. The tools can be accessed at http://hvdr.bioinf.wits.ac.za/SmallGenomeTools, and the source code is available online at https://github.com/DrTrevorBell/SmallGenomeTools. MDPI 2015-02-16 /pmc/articles/PMC4353916/ /pubmed/25690798 http://dx.doi.org/10.3390/v7020781 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bell, Trevor G.
Kramvis, Anna
Bioinformatics Tools for Small Genomes, Such as Hepatitis B Virus
title Bioinformatics Tools for Small Genomes, Such as Hepatitis B Virus
title_full Bioinformatics Tools for Small Genomes, Such as Hepatitis B Virus
title_fullStr Bioinformatics Tools for Small Genomes, Such as Hepatitis B Virus
title_full_unstemmed Bioinformatics Tools for Small Genomes, Such as Hepatitis B Virus
title_short Bioinformatics Tools for Small Genomes, Such as Hepatitis B Virus
title_sort bioinformatics tools for small genomes, such as hepatitis b virus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353916/
https://www.ncbi.nlm.nih.gov/pubmed/25690798
http://dx.doi.org/10.3390/v7020781
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