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Hybrid resection of a giant thigh plexiform neurofibroma
PRESENTATION OF CASE: Authors present a case of a 55 year old patient with Type 1 neurofibromatosis (NF1) and a very large right thigh plexiform neurofibroma. The patient had increasing difficulty with mobilization due to this enlarging bulky mass. Preoperative embolization reduced the bleeding risk...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353941/ https://www.ncbi.nlm.nih.gov/pubmed/25603483 http://dx.doi.org/10.1016/j.ijscr.2015.01.015 |
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author | Kolker, S. Wunder, J.S. Roche-Nagle, G. |
author_facet | Kolker, S. Wunder, J.S. Roche-Nagle, G. |
author_sort | Kolker, S. |
collection | PubMed |
description | PRESENTATION OF CASE: Authors present a case of a 55 year old patient with Type 1 neurofibromatosis (NF1) and a very large right thigh plexiform neurofibroma. The patient had increasing difficulty with mobilization due to this enlarging bulky mass. Preoperative embolization reduced the bleeding risk at surgery allowing successful gross resection of the mass by a multidisciplinary surgical team. Limb function was restored to normal. DISCUSSION: Massive plexiform neurofibromatosis is a rare expression of von Recklinghausen's disease or NF1. These large masses result in severe disfigurement and significant functional disability. They are extremely vascular and there is potential for malignant transformation. CONCLUSION: These massive tumors require complex preoperative, intraoperative and postoperative management strategies with involvement from a multidisplinary team. We discuss the challenges of surgical intervention and to discuss the current literature. |
format | Online Article Text |
id | pubmed-4353941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-43539412015-03-31 Hybrid resection of a giant thigh plexiform neurofibroma Kolker, S. Wunder, J.S. Roche-Nagle, G. Int J Surg Case Rep Case Report PRESENTATION OF CASE: Authors present a case of a 55 year old patient with Type 1 neurofibromatosis (NF1) and a very large right thigh plexiform neurofibroma. The patient had increasing difficulty with mobilization due to this enlarging bulky mass. Preoperative embolization reduced the bleeding risk at surgery allowing successful gross resection of the mass by a multidisciplinary surgical team. Limb function was restored to normal. DISCUSSION: Massive plexiform neurofibromatosis is a rare expression of von Recklinghausen's disease or NF1. These large masses result in severe disfigurement and significant functional disability. They are extremely vascular and there is potential for malignant transformation. CONCLUSION: These massive tumors require complex preoperative, intraoperative and postoperative management strategies with involvement from a multidisplinary team. We discuss the challenges of surgical intervention and to discuss the current literature. Elsevier 2015-01-09 /pmc/articles/PMC4353941/ /pubmed/25603483 http://dx.doi.org/10.1016/j.ijscr.2015.01.015 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
spellingShingle | Case Report Kolker, S. Wunder, J.S. Roche-Nagle, G. Hybrid resection of a giant thigh plexiform neurofibroma |
title | Hybrid resection of a giant thigh plexiform neurofibroma |
title_full | Hybrid resection of a giant thigh plexiform neurofibroma |
title_fullStr | Hybrid resection of a giant thigh plexiform neurofibroma |
title_full_unstemmed | Hybrid resection of a giant thigh plexiform neurofibroma |
title_short | Hybrid resection of a giant thigh plexiform neurofibroma |
title_sort | hybrid resection of a giant thigh plexiform neurofibroma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353941/ https://www.ncbi.nlm.nih.gov/pubmed/25603483 http://dx.doi.org/10.1016/j.ijscr.2015.01.015 |
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