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Metabolomics integrated elementary flux mode analysis in large metabolic networks

Elementary flux modes (EFMs) are non-decomposable steady-state pathways in metabolic networks. They characterize phenotypes, quantify robustness or identify engineering targets. An EFM analysis (EFMA) is currently restricted to medium-scale models, as the number of EFMs explodes with the network...

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Detalles Bibliográficos
Autores principales: Gerstl, Matthias P., Ruckerbauer, David E., Mattanovich, Diethard, Jungreuthmayer, Christian, Zanghellini, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354105/
https://www.ncbi.nlm.nih.gov/pubmed/25754258
http://dx.doi.org/10.1038/srep08930